Principal Research Scientist, I

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

AbbVie is looking for talented Protein Biochemists with strong Protein Sciences expertise to join our team at our headquarters in the Chicago area. This exciting role is central to advancing small molecule drug discovery across a variety of disease areas using innovative biochemical strategies. As an integral member of our team, you will drive projects and collaborate across functions to develop robust and scalable protein workflows and address strategic questions in support of key drug discovery activities, including assay development, screening, structure-based design, and exploratory biology.
Success in this position requires a solid foundation and proven track record in Protein biochemistry and related fields, good understanding and applications of computational protein design tools, and strong collaborative skills.

Key Responsibilities:

• Innovate and lead experimental plans to address essential questions about protein functions and overcome challenges in generating protein /protein complexes with low yield, aggregation issues.
• Enhance and implement best practices in protein expression, purification, and characterization to support drug discovery programs.
• Design complex protein constructs and guide purification processes to enable cutting-edge biochemical/biophysical assays and structural biology research.
• Serve as the technical expert in protein production, utilizing advanced chromatographic techniques on AKTA systems.
• Effectively use of advanced computational tools and the development of novel approaches to strengthen our program capabilities.
• Work closely with project teams to identify and solve key questions within the domain of protein biochemis