Research Associate, Imaging Development

Description

A little about us:

The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention.

We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.

Job Summary: 

We are seeking a self-motivated individual with experience in molecular and cellular neurobiology to join our interdisciplinary research group as a Research Associate. This position is open to experienced laboratory scientists seeking a position within a translational research setting with a focus on spatial transcriptomics projects in human brain tissue in a dynamic team-based environment. Projects aim to generate transcriptome-scale maps in various regions of the human brain to understand differences in spatial gene expression in normal development and aging as well as in neuropsychiatric disorders. 

Overview of Duties:

The position participates in experimental design, conducts experiments and performs computational analysis to generate and interpret data. 

Additional Responsibilities include:

· Assist with brain tissue dissections

· RNA-seq library construction

· Cryosectioning of tissue

· Single molecule fluorescence in-situ hybridization

· Histological and immunofluorescence staining

· Confocal imaging and slide-scanning

· Histological and immunofluorescence image analysis

· Generate figures, organize data, present and explain data

· Manage ordering and reagent inventories

· Supervise experiments, provide training to junior staff members

· Other duties as assigned

Requirements

 Minimum Qualifications:

· Bachelors degree in Neuroscience or a related field of biology required. Masters degree preferred

· Minimum 3 years full time molecular biology or computational biology experience is required

Familiarity with any of the following topics or techniques is a plus:

· molecular/cellular biology

· confocal microscopy

· next generation sequencing

· Programming in MATLAB, R or Python

· Image analysis

· Flow cytometry

· Single cell sequencing

· Spatial transcriptomics

· Neuroanatomy

Special Knowledge, Skills and Abilities:

Initiative to learn new methods and perform work efficiently and carefully are essential.Excellent organizational and communication skills also required.

Physical Requirements:· Remaining in a seated or standing position for extended periods of time;· Reaching and grasping to manipulate objects with fingers;· Mobility, including the ability to maneuver around a laboratory setting including the ability to move materials weighing up to 25 pounds;· Communication skills using the spoken and written word; · Having the ability to receive detailed information through oral communication;· All other physical demands in a standard laboratory environment.   ** If accommodations are needed due to pregnancy or a disability, please contact jobs@libd.org

Benefits:  We offer a comprehensive benefits package which includes medical, dental and vision insurance, 403B with employer matching, paid time off, wellness programs, short term and long term disability and much more. More information can be found here: https://www.libd.org/careers/benefits/ 

Vaccination Requirement:  As of September 18, 2023, LIBD has simplified its COVID vaccination policy. All incoming students and employees must have received at least on