Global Payroll Manager

About Us

Hippocratic AI has developed the only safe, safety-focused Large Language Model (LLM) for healthcare, resulting in the only autonomous patient-facing clinical agents in the industry. We are delivering abundance for the first time in healthcare by bringing deep clinical expertise to every human. No other technology has the potential to have this level of global impact on health. Come join the most capitalized healthcare AI company with the most deployed customers and the broadest platform of applications. Our highly mission-oriented team, coupled with innovative partners like the Cleveland Clinic, Baylor Scott & White, Northwestern, Wellspan, HCA, and Oschner, is building the most transformative company in healthcare in history.

Why Join Our Team

• Reinvent healthcare with AI that puts safety first. We’re building the world’s first healthcare-only, safety-focused LLM — a breakthrough platform designed to transform patient outcomes at a global scale. This is category creation.

• Work with the people shaping the future. Hippocratic AI was co-founded by CEO Munjal Shah and a team of physicians, hospital leaders, AI pioneers, and researchers from institutions like El Camino Health, Johns Hopkins, Washington University in St. Louis, Stanford, Google, Meta, Microsoft, and NVIDIA.

• Backed by the world’s leading healthcare and AI investors. We recently raised a $126M Series C at a $3.5B valuation, led by Avenir Growth, bringing total funding to $404M with participation from CapitalG, General Catalyst, a16z, Kleiner Perkins, Premji Invest, UHS, Cincinnati Children’s, WellSpan Health, John Doerr, Rick Klausner, and others.

• Build alongside the best in healthcare and AI. Join experts who’ve spent their careers improving care, advancing science, and building world-changing technologies — ensuring our platform is powerful, trusted, and truly transformative

About the Role

As the Global Payroll Manager, you will hold end-to-end ownership for the company’s payroll operations, optimizing processes to strategically support Hippocratic AI’s next phase of growth. This role requires extensive cross-functional collaboration with HR, Accounting, and Legal to ensure timely, accurate, and compliant payruns and regulatory filings across all jurisdictions. Over the long term, you will be responsible for building and leading a high-performance payroll operations team to scale with the global business.

What You'll Do

Payroll Processing & Compliance:

• Own end-to-end payroll process for exempt and hourly employees across all global entities.

• Own payroll setup for new hires and ensure all employee changes (comp, deductions, benefits, garnishments, tax elections, etc.) are processed accurately and on time.

• Partner with the India Accounting team to ensure accurate and timely payroll administration for India-based employees, including support on local compliance requirements.

• Manage payroll administration through Employer of Record (EOR) providers across global jurisdictions and support payroll readiness for expansion into new countries/states.

• Ensure compliance with all applicable wage and hour regulations, payroll tax registration and filing requirements across relevant U.S. jurisdictions, and maintain complete payroll records aligned with legal and tax obligations.

• Develop, implement, and maintain robust payroll, time-off, leave, and workers’ compensation procedures and guidelines; monitor compliance and ensure operational accuracy.

• Drive payroll controls and documentation; serve as the payroll compliance owner (including SOX-ready controls, where applicable).

Audits, Reporting & Controls

• Perform pre- and post-payroll audits, prepare reconciliations, and conduct payroll variance analysis each cycle to proactively identify and resolve discrepancies.

• Own monthly/quarterly/annual payroll reconciliations and reporting, including:

  • W-2 and 1099 preparation

  • Quarterly/annual amendments

  • 401(k) testing and reconciliations

  • Payroll tax filings and reporting

• Manage incentive and equity payroll processing (ISOs, NQSOs), ensuring accurate withholding, reporting, and tax-related submissions, including estimated tax obligations when applicable.

• Liaise with auditors and coordinate payroll tax, benefits, and compliance audits; ensure documentation readiness and issue resolution.

Financial Reporting & Close

• Partner with Accounting to support month-end close processes, including creati