Executive Director, U.S. Medical Science Liaison

Company Overview:

Dyne Therapeutics is discovering and advancing innovative life-transforming therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE™ platform, Dyne is developing targeted therapeutics that deliver to muscle and the central nervous system (CNS). Dyne has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD) and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. For more information, please visit https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook. 

Role Summary:

Medical Science Liaisons (MSLs) are the field-based extension of our Medical Affairs team. MSLs are scientifically trained professionals who possess strong clinical and/or scientific backgrounds whose role is to be a resource of balanced, impartial, and scientifically rigorous information to our patients, clinical study sites, study personnel and Key Opinion Leaders (KOLs). The Executive Director of the U.S. MSL team will be responsible for leading a team of U.S.-based MSLs that will facilitate enrollment in company sponsored studies, engage with clinical study sites, study personnel, KOLs, and other health care providers with scientific exchange and clinical support for investigational products. The MSL Team Leader will pair the changing needs of healthcare professionals with available Dyne resources. The U.S. MSL Team Leader will work under the guidance of the Global Head of Medical Affairs and in close collaboration with the Global Medical Affairs Leads (GMALs), EU Medical Affairs team, Clinical Operations, Clinical Development teams and Patient Advocacy.

This role is based in the U.S.

Primary Responsibilities Include:

• Build, train and lead an agile U.S. MSL Team and ensure strategic alignment with all field activities globally
• Stimulate and motivate people and teams to develop and execute medical excellence and medical leadership
• Develop and demonstrate a thorough working knowledge of Company, investigational products, and disease state, as well as competitors and treatment landscape
• Develop strategic and tactical KOL plans to enhance awareness of Dyne within the medical community and educate healthcare professionals on Dyne’s platform and portfolio
• Involvement in the scientific and medical communication strategy and in any non-promotional material review as per procedure until market authorization (MA) is granted. Once the MA is granted, this person is responsible for the scientific review of any promotional material
• Ensure the dissemination of transparent, fair-balanced medical, scientific, and clinical information, knowledge, and literature, within corporate guidelines, for healthcare provider education in a timely, compliant, ethical, and customer-focused manner
• Ensure MSL team serves as liaison between clinical investigators and internal stakeholders in support of clinical research activities (e.g., company sponsored, investigator initiated studies)
• Develop, maintain, and manage collaborations with regional and national KOLs, investigators, study staff (site staff and CRO staff)
• Identify and build collaborations with KOLs for medical education and potential clinical research opportunities
• Think strategically to translate medical/clinical insights of treatment paradigms into growth opportunities, process improvement and driving competitive advantage
• Provide field-based medical and scientific support to answer unsolicited questions about Company, investigational products, and associated disease states
• Deliver high quality educational presentations in a variety of settings and obtain feedback that can be disseminated throughout the organization
• Participate in therapeutic advisory groups or Steering Committees and internal project teams, as appropriate
• Gather and disseminate competitive intelligence from multiple sources, internally and externally
• Attend regional / local conferences on Company’s behalf to provide feedback on current landscape, competitive landscape and continued cultivation of relationships
• Provide feedback on specific sites and regional trends/thoughts/paradigms to identify and/or inform potential protocol amendments, accrual barriers, patient/study subject identification
• Complete accurate and timely administrative reports, projects, and other required documentation

Education and Skills Requirements:

• Advanced scientific degree or equivalen