Advisor/Sr. Advisor- Analytical Chemistry - Genetic Medicines (SMDD)

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Synthetic Molecule Design and Development (SMDD) organization is responsible for the development of synthetic drug substances and drug products from the pre-clinical phase through commercialization. Our scientists and engineers develop innovative technical solutions to advance an exciting portfolio that includes small molecules, synthetic peptides, oligonucleotides, and other emerging therapeutic modalities. By cultivating a hardworking, culturally diverse workforce that exhibits deep technical expertise, SMDD delivers on these responsibilities and helps bring the next generation of life-changing medicines to patients.  

Our team is seeking rising technical scientists who are innovative and motivated to apply their strong foundation in analytical sciences to develop robust control strategies, enable clinical trials, regulatory submissions, and new product commercialization. In this role you will have the opportunity to lead analytical efforts within a multidisciplinary team consisting of chemists, formulation scientists, and engineers while offering access to world-class capabilities for pharmaceutical product development.  This technical, lab-based role is at the early phase interface with our Lilly Genetic Medicines (LGM) discovery team and will be co-located at our new research facility opening in Boston Seaport in mid-2024.  This role will emphasize identification of emerging analytical needs to enable the LGM portfolio, including development and execution of research plans with a cross functional team to help accelerate programs and facilitate technical transfer to the early phase clinical supply team located in Indianapolis.    

Responsibilities: 

Top candidates for this position will be expected to:  

• Apply high-resolution mass spectrometry in the structural and biophysical characterization of therapeutic oligonucleotides and bioconjugates. 

• Drive the implementation of technical solutions and analytical strategies to enable synthetic chemistry, process engineering, formulation design, and continuous manufacturing. 

• Creative mindset with the ability to craft a vision for a team of innovative analytical chemists, adopting and implementing new technologies to accelerate and deliver the genetic medicines <