Executive Director, Oncology Head, Translational Development

Working with Us
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Context

Bristol Myers Squibb is an integrated global biopharmaceutical company engaged primarily in the discovery, development and commercialization of novel therapies for the treatment of cancer, cardiovascular and inflammatory diseases.  BMS R&D is at a critical and exciting phase of development. As it expands and integrates its portfolio, there is an opportunity for a dynamic and resourceful individual to lead our oncology efforts in Translational Development at our sites in New Jersey or Cambridge, MA. 

Translational Development at BMS

Translational Development is part of the Global Research organization in BMS and leads late stage translational research and development activities for the late-stage portfolio. Translational Development supports all therapeutic areas (heme/onc, immunology, cardiovascular, and neuroscience). This group integrates scientific, strategic and business insights to lead the development of translational strategies at the franchise level and implements them in project teams to maximize the potential of BMS drugs for patients. 

Summary

Reporting to the VP, Translational Development, the incumbent will be part of the translational team based in either Cambridge, MA or Princeton/Madison, NJ and will help develop translational disease and asset strategies in solid tumor disease areas for assigned programs for approval or life-cycle management of the BMS pipeline (excluding CART). Key responsibility of this role is to lead the breast disease area strategy and a cross functional team of asset and disease scientists with deep disease, drug development and business knowledge working closely with discovery and early development teams, late clinical development as well as the broader oncology TD team

Technical Skills 

• In-depth understanding of Oncology, especially Breast Cancer or Prostate, clinical landscape, evolving therapy, competitive landscape

• Strong understanding of clinical, translational and mechanistic data with therapeutics development

• Strong background in genetics, cancer biology and/or immunology

• Experience in deploying biomarkers for trial design including MRD guided designs, endpoints

• Experience in reverse translation with discovery experience a plus

• Experience in disease strategy development working cross-functionally

• Understanding of late-stage drug and translational development process

• Proven track record of drug submissions, approvals, regulatory interactions and label negotiations

• Proven ability to work with global disease teams to develop strategies to support life cycle management efforts tailored to regional markets (i.e., US, EU, CAN)

• Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, strategic communications, literature/market/pt segment analyses 

• Proven success in spearheading collaborative scientific initiatives internally and with academic partners

Responsibilities

• Leads the development of disease and asset specific translational annual goals and objectives for Translational Development (for internal /external, translational collaboration, compound specific plans, open research questions etc)

• Builds disease area specific long term translational strategy and implementation across portfolio 

• Assists in developing and maintaining group budget and workforce plan 

• Represents Translational Development in cross-functional Strategy Teams an