Manager/Sr. Manager, Commercial Global Supply Chain Planner

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on
 
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible. 
 
Together we define white space, push boundaries and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.

Affiliate Overview

Calcilytix Therapeutics, an affiliate within BridgeBio Pharma, is developing encaleret, a negative allosteric modulator of the calcium-sensing receptor (CaSR) for the treatment of Autosomal Dominant Hypocalcemia Type 1 (ADH1), a genetic cause of hypoparathyroidism. Encaleret is currently being evaluated in a Phase 3 clinical study and has received Orphan Drug Designation from the US FDA, EMA, and PMDA as well as Fast Track Designation from the US FDA. Results from the Phase 2b clinical study of encaleret in patients in ADH1 were published in the New England Journal of Medicine.

What You'll Do

The Manager/Sr. Manager, Commercial Global Supply Chain Planner will be responsible for developing comprehensive supply plans to support commercial forecasts, optimizing inventory positions, contributing to the S&OP process, and supporting supply chain launch readiness efforts for new commercial products. Collaboration with internal and external partners, including Commercial demand planning, CMC teams, and CMOs / CPOs, will be instrumental in successfully developing a global supply plan that supports market demand and drives supply chain efficiency. 

Responsibilities

Supply Planning Process / Launch Readiness 

• Utilize and optimize existing supply planning tools and processes to drive global supply chain effectiveness
• Reconcile global supply and demand, and collaborate closely with the demand planner to align forecasts
• Develop an accurate production plan for all key components of the pharmaceutical supply chain (including but not limited to Drug Substance/API, Drug Product, packaging, and labeling)
• Create a Master Production Schedule (MPS) for all suppliers, including Contract Manufacturing Organizations (CMOs) & Contract Packaging Organizations (CPOs), and support communication of the MPS regularly
• Determine and adjust safety stock levels for finished goods at the Third Party Logistics (3PLs) warehouse, achieve inventory targets, and mitigate stock-outs
• Develop ramp-up supply plans to support new commercial product introductions  

Inventory Reconciliation and Reporting 

• Responsible for tracking inventory levels, generating reports to provide insights into inventory performance, and identifying areas for improvement
• Collaborate with external parties (CMOs / CPOs / 3PLs) and internal stakeholders (commercial and finance) on monthly inventory reporting and reconciliation
• Monitor inventory shelf-life and develop supply plans that mitigate expiration loss 

Sales & Operations Planning (S&OP) Support:  

• Provide essential inputs and support to ensure alignment between supply and demand, contributing to the development of robust and effective S&OP strategies
• Present proposed supply plans and insights on supply plan accuracy/production adherence, and inventory management to the executive team 

Item Number Process Owner:  

• Own the new item number introduction and management process
• Ensure the Standard Operation Procedure is followed for all item number additions, changes, and obsolescence
• Collaborate with stakeholders to ensure accurate and timely implementation of item numbers for the new commercial product 

Where You'll Work

This is a role that can either be based in the