Principal Scientist I, Cellular/Functional Biology

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Discovery Biotherapeutics and Genetic Medicine (BGM) at Abbvie is seeking a highly motivated Principal Research Scientist to join the Cell and Functional Biology group at the AbbVie Bioresearch Center (ABC) site based in Worcester, MA.  This role will be responsible for the design and execution of screening strategies employed to advance promising biotherapeutics from early exploration through lead optimization.  Close partnerships with cross-functional colleagues will be required to drive transformative ideas to the clinic. The ideal candidate should possess experience in large molecule screening strategy design including vitro cell-based assays, with a strong experience in functional assay development and high-throughput screening.

Job Responsibilities:

• Develop in vitro functional assays leveraging diverse signaling pathways to transition early therapeutic ideas into enabled biotherapeutics campaigns.
• Design and employ strategic screening funnels for biotherapeutic discovery campaigns, performing detailed analysis of complex data sets for key insights guiding decision-making processes in research projects.
• Identify and integrate cutting-edge technologies and methodologies into screening and assay development, anticipating future trends in drug discovery.
• Foster strong cross-functional collaborations with therapeutic area partners to promote the generation of innovative ideas and solutions which support organizational objectives.
• Present and explain research findings and strategies clearly and effectively, preparing scientific reports, publications, and presentations for varied audiences.
• Demonstrate scientific excellence through dedication to multiple proje