Research Lab Tech I (Margeta)

Site: Massachusetts Eye and Ear Infirmary

 

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

 

 

Job Summary

Summary - Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data.
Does this position require Patient Care? No
Essential Functions
-Perform laboratory experiments following established protocols and procedures.
-Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
-Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
-Record experimental data accurately and maintain organized records of procedures, protocols, and results.
-Compile and analyze data using appropriate statistical and analytical methods.
-Assist in data interpretation and presentation, contributing to research findings and reports.

 

Qualifications

Education
Bachelor's Degree Related Field of Study required

Can this role accept experience in lieu of a degree?
Yes

Licenses and Credentials

Experience
Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred

Knowledge, Skills and Abilities
- Strong theoretical and practical knowledge of laboratory techniques and procedures.
- Familiarity with common laboratory equipment and instruments used in research experiments.
- Proficiency in data collection, analysis, and scientific software tools.
- Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
- Strong problem-solving skills and the ability to troubleshoot technical issues.
- Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

 

Additional Job Details (if applicable)

POSITION SUMMARY:

We are seeking a highly motivated research technician to join our laboratory investigating how neuroinflammation contributes to the pathogenesis of glaucoma, the leading cause of irreversible blindness worldwide. Our research focuses on understanding the molecular mechanisms by which immune responses shape disease progression in the retina and optic nerve.

Specifically, the lab studies the roles of microglia and macrophages in glaucoma, as well as their crosstalk with other cells in the retinal and optic nerve microenvironment. Using a combination of in vivo models, histology, molecular biology, and advanced imaging approaches, we aim to define how neuroimmune interactions influence neuronal vulnerability and degeneration. For more information about our current work and past publications, please feel free to visit our lab website at https://www.margetalab.org/.

This position is ideal for candidates interested in neuroscience, immunology, or vision research, and provide strong training for those considering graduate, medical, or MD-PhD programs. Technicians will receive close mentorship and opportunities to contribute meaningfully to ongoing projects.

ESSENTIAL RESPONSIBILITIES:

Assist with ongoing research projects investigating neuroinflammatory mechanisms in glaucoma. Perform laboratory experiments involving retinal and optic nerve tissue, including tissue processing, sectioning, and histological analyses. Conduct immunohistochemistry, immunofluorescence, and microscopy to assess microglia, macrophages, and other cell populations. Support in vivo/in vitro/ex vivo studies, including animal handling, sample collection, and basic experimental procedures (with training provided). Maintain accurate and detailed experimental records, protocols, licenses, expense reports, and data organization. Analyze and quantify imaging or molecular data using Fiji (ImageJ). Assist with general laboratory maintenance, including reagent preparation, inventory management, and equipment upkeep. Collaborate closely with faculty, postdoctoral fellows, and other lab members on team-based projects.

QUALIFICATIONS:

Bachelor’s degree in the biological sciences, physical sciences, or a related field is require