Cellular Therapy Specialist (FT, Days) - Center City

Job Details

*Position may be required to work late hours pending length of procedures.
The Clinical Laboratory for Cellular Therapy (CLfCT) is a FACT accredited facility for processing stem cell transplant & donor lymphocyte collections and processing cellular therapy products for investigatory clinical trials including CD34 selections, CAR-T and TIL infusions and manufacturing Immune Effector Cell Therapies (IECT). Cell Therapy Specialists will perform innovative techniques such as cell counting, flow cytometry for lymphocyte subsetting, plasma reduction, RBC reduction, cryopreservation and will become proficient in the use of cell manufacturing equipment such as CliniMACS PLUS, CliniMACS PRODIGY, Quantum Bioreactor for cell expansion. Cellular Therapy Specialists will participate in many sponsor-initiated clinical trials involving a variety of cell-based therapeutics. As the field of cell therapy continues to expand, Cellular Therapy Specialists will also participate in the development of cutting edge protocols and procedures for manufacturing new products. Cellular Therapy Specialists participate in the quality management program and ensure daily operations are in compliance with regulatory/accredidation requirements including FACT, FDA, CLIA, CAP and JCAHO.

Job Description

• Processing, storage and infusion preparation of hematopoietic stem cells, donor lymphocytes, immune effector cells & other cellular therapy products in support of the Blood and Marrow Transplant Program

• Training & maintaining competencies of immune cell analysis via flow cytometry, plasma/RBC reductions, cell selections, cell expansions, cryopreservation, thawing and quality control testing as part of product release

• Receiving, Handling, Storing, Transporting & Administering externally manufactured products

• Manufacturing novel cellular therapy products (CAR-T, TILs, Mesenchymal Stem Cells, etc.) for Jefferson Investigator-initiated clinical trials

• Developing & Implementing new research protocols, laboratory SOPs & validation assays in collaboration with Jefferson Physicians/Investigators for expanding cellular therapeutic needs

• Maintaining patient records per GDPs both on paper and in computer databases

• Performing environmental monitoring of laboratory spaces, equipment and supplies

• Participating in On-call service and Responding to Alarms Notifications regarding patient sample storage

• Interacting with Patients, Physicians, Nursing Staff, Quality Assurance Staff and Administrative teams

• Interacts with co-workers, visitors, and other staff consistent with the core values of the Hospital

• Educational/Training Requirements: Bachelor's Degree in biology, medical technology, laboratory science or equivalent scientific field required.

  Experience Requirements: Minimum 1 year experience working in a clinical or research lab or equivalent GMP/GLP setting (Required). Minimum 1 year experience working with tissue culture techniques, flow cytometry and/or molecular biological assays (Preferred).  Experience using MS Office including Word, Excel (Required).

Work Shift

Weekend Day (United States of America)

Worker Sub Type

Regular

Employee Entity

Thomas Jefferson University Hospitals, Inc.

Primary Location Address

1100-04 Walnut Street, Philadelphia, Pennsylvania, United States of America

Nationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research.