Scheduled Hours

40

Position Summary

The Vindigni laboratory studies DNA replication and repair, and the roles of these pathways on cancer initiation, progression and response to chemotherapy and immunotherapy. We offer a unique environment that combines biochemical, cellular, and structural approaches, making it an ideal setting for training staff and students interested in exploring the mechanisms that maintain genome integrity. We are among the few labs worldwide that integrate cellular and electron microscopy techniques to investigate changes in replication fork dynamics at the single-molecule resolution.

The ideal candidate should be highly motivated and interested in learning cutting-edge techniques to study the impact of DNA damaging chemotherapy on genome stability and DNA replication fork progression. Work in the lab includes culturing human cancer cell lines and learning techniques to monitor DNA damage and cell viability.

Position assists with the technical aspects of these studies and experiments including documentation and preparation of materials for electron microscopy experiments. In addition to experimental assistance, candidate will be responsible for helping with general lab maintenance, cleaning, stocking, and organization. Opportunities for publication will be available.

Job Description

Primary Duties & Responsibilities:

For information on specific projects in the lab, please see: https://vindignilab.wustl.edu/. 

• Assists with research studies, experiments and assays, including collection of data, preparation of solutions and setup and maintenance of equipment.

• Assists with cellular assays to monitor DNA damage and cell viability, as well as with preparation of samples for electron microscopy experiments.

• Performs data entry and maintains data files on research.

• Prepares tissue cultures, reagents, probe tests, etc.

• Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions.

• Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.

• Assists with general lab maintenance and cleaning.

• Performs other duties as assigned.

Working Conditions:

• This position works in a laboratory environment with potential exposure to biological and chemical hazards. 

• The individual must be physically able to wear protective equipment and to provide standard care to research animals.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education:

Bachelor’s degree or combination of education and/or experience may substitute for minimum education.

Certifications:

No specific certification is required for this position.

Work Experience:

No specific work experience is required for this position.

Skills:

Not Applicable

Driver's License:

A driver's license is not required for this position.

More About This Job

The ideal candidate will have up to one year of experience in a laboratory setting.

Preferred Qualifications

Education:

No additional education beyond what is stated in the Required Qualifications section.

Certifications:

No additional certification beyond what is stated in the Required Qualifications section.

Work Experience:

No additional work experience beyond what is stated in the Required Qualifications section.

Skills:

Communication, Detailed Reports, Laboratory Instrumentation, Laboratory Research, Software Program, Working Independently

Grade

R06-H

Salary Range

$16.92 - $26.44 / Hourly

The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Questions