Senior Downstream Process Engineer

Who We Are:

Antheia is a science and technology company developing next generation plant-inspired medicines. Applying synthetic biology, genomics, bioinformatics, data science, and fermentation, we harness the most beneficial molecules from plants to create active pharmaceutical ingredients in more controlled and economical ways. We are a close-knit team inspired by the possibilities of delivering transformative technologies and breakthrough science to change the course of medicine. We value our people as our most important resource and are always looking for talented individuals who can make valuable contributions to our efforts.

Job Description: 

Antheia is seeking an experienced Senior Process Engineer to join our Downstream Processing team, where you will play a critical role in developing innovative, scalable processes to separate and purify bio-derived Key Starting Materials and APIs. You'll have the opportunity to work hands-on from bench to pilot scale, solving complex challenges that bring groundbreaking science from the lab to manufacturing. From designing and optimizing processes to supporting technology transfers, you'll directly contribute to delivering high-quality, sustainable products. You'll lead experiments, analyze data, and guide the procurement and maintenance of equipment essential for scaling up processes. This role offers the chance to collaborate cross-functionally with experts in Biology, Analytics, Operations, Manufacturing, and Regulatory teams.  

If you're ready to tackle meaningful challenges and drive innovation, we invite you to explore this opportunity with us. 

Responsibilities: 

• Develop DSP processes that are shown to be scalable, meet timelines and COGs and scale processes 

• Support tech transfer projects to manufacturing providing scalable data to determine equipment fit and process flow. 

• Establish key unit op parameters based on robustness to meet specifications and recovery yields 

• Equipment identification and procurement, for bench to Pilot Scale Process Development and track equipment costs for budgeting. 

• Provide equipment SOPs, maintenance and ensure continuous DSP processing capabilities 

• Characterize downstream process streams and identify parameters that impact unit op behavior, yield and purity 

• Maintain mass balance data for all DSP processes and ensure mass balance closure. Provide heat and energy balances when needed. 

• Experimental design and data analysis 

• Provide PFDs, P&IDs and basis of design for DSP processes when required 

• Provide and maintain DSP documentation to support process analysis and tech transfers 

• Provide technical leadership and mentorship to engineers, which includes identifying and tracking KPIs as well as career development 

• Comply with safety protocols and ensure the safety of co-workers 

• Comply with Regulatory and DEA requirements when required for handling, disposal and documentation 

• Support project teams to deliver on project goals 

• Perform other duties as assigned1 

 

Qualifications: 

• B.S. in Chemical Engineering (or related engineering discipline) with a minimum of 5 years of industry experience specifically within downstream processing. 

• Hands on experience with downstream unit operations and proven process scale up from bench to pilot scale (300-500L); this includes scale down for troubleshooting. 

• Experience with equipment procurement, commissioning, authoring SOPs, training and maintenance and repairs. 

• Experience modeling process predictions to improve process development efficiencies. 

• Prior leadership experience, with at least 1 direct report 

• Available to travel ~10% annually, both domestic and international 
• Must be able to l