Job Description​

Saint Luke’s Cancer Institute and Saint Luke’s Marion Bloch Neuroscience Institute seek a Medical Director of Neuro-Oncology to lead and expand the neuro-oncology clinical program and clinical research portfolio. The director will provide clinical leadership, oversee existing brain tumor clinical trials, and develop new investigator-initiated studies and industry collaborations to broaden therapeutic options for patients. The director will collaborate with multidisciplinary neuroscience teams, including two designated oncologic neurosurgeons, dedicated neuro–radiology, neuro-pathology and a neuro-oncologist joining in July 2026. This is an academic clinical appointment commensurate with experience.

Vision for Neuro-Oncology at Saint Luke’s:

Saint Luke’s is committed to developing a premier neuro-oncology program that delivers exceptional patient-centered care while advancing the science and practice of neuro-oncology. The  goal is to become the leading neuro-oncology program in the region, with a clear trajectory toward national recognition for clinical excellence, innovation, and leadership in neuro-oncology clinical research.

A central pillar of the neuro-oncology strategy is the expansion and diversification of the clinical trials portfolio. The Institute seeks to become a regional hub for brain tumor clinical trials, ensuring that patients across the region have access to advanced therapies locally.

With strong leadership, the neuro-oncology program will develop a trial-focused culture in which clinical research is integrated into routine care and trial availability becomes a defining feature of the patient experience.

The Institute maintains a robust academic mission, fostering mentorship, faculty development, and training for future leaders in neuro-oncology. With established neurosurgical oncology expertise and planned expansion of neuro-oncology faculty, the program is positioned for thoughtful growth while maintaining excellence.

Ultimately, Saint Luke’s Cancer Institute in partnership with the Marion Bloch Neuroscience Institute aims to be recognized nationally as a center known for:

• High-quality, compassionate neuro-oncology care

• Strong clinical trial enrollment and innovation

• Multidisciplinary excellence

• Leadership in programmatic growth and outcomes

The Director of Neuro-Oncology will play a pivotal role in shaping and executing this vision, serving as a clinical leader, program builder, and advocate for innovation on behalf of patients and the institution.

Key Responsibilities:

• Provide clinical care for adult brain tumor patients in inpatient and outpatient settings; maintain high standards of patient-centered care and multidisciplinary coordination.

• Provide strategic leadership for neuro-oncology programmatic development, quality improvement, strategic planning, and cross-department collaboration

• Assume primary oversight of the active neuro-oncology clinical trials: ensure regulatory compliance, participant safety, data integrity, and timely accrual.

• Expand the clinical trial portfolio by pursuing investigator-initiated trials, fostering relationships with industry sponsors, and collaborating with institutional research offices and cancer research networks. Dedicated research coordinators and grant-writing support are available.

• Mentor and supervise neuro-oncology faculty, advanced practice providers, and research staff, and support education and training activities.

• Participate in weekly tumor board, multidisciplinary clinics, and community/outreach efforts to raise the program’s profile and referral base.

Required Qualifications:

• MD, DO, or equivalent degree (or MD/PhD) with board certification (or eligibility) in Neurology, Medical Oncology, or related specialty and fellowship training in Neuro-Oncology.

• Active medical license in Missouri (or eligibility to obtain).

• Several years (typical: 3+ years) of post-fellowship clinical experience in neuro-oncology with demonstrated clinical trial involvement and experience managing or serving as PI on clinical studies. We are seeking a candidate with demonstrable experience initiating,  or leading clinical trials and with a track record of patient accrual and site/study leadership.

• Strong leadership, interpersonal, and communication skills with a collaborative approach to multidisciplinary care.

Preferred Qualifications

• Experience growing or directing an academic neuro-oncology program or leading a clinical trials portfolio.

• Prior experience with invest