Jobs and Careers

Sr Technical Product Manager

US Remote, United StatesRemotefull_timeVerifiedPosted 14 Jul 2026

💰 $160,000/yr($120,000/yr – $160,000/yr)

About the role

Position Summary

As a key member of the product management group, you partner with and enable other product managers to execute on their roadmaps by providing deep technical expertise, managing complex cross-team dependencies, and translating technical constraints into product strategy. This role is designed for a technically sophisticated product manager who thrives in supporting ambitious engineering initiatives, making informed technical tradeoffs, and influencing outcomes across multiple product areas in highly ambiguous, multi-team environments.

You will work across a portfolio of platform and infrastructure products, partnering closely with engineering leaders and product managers to navigate modernization efforts, system reliability improvements and architecture evolution. Success requires the ability to deeply understand system architecture and technical constraints, establish clear success metrics, collaborate effectively with peer product managers and ensure alignment across interconnected initiatives.

Key Responsibilities

Partner with product managers to understand their roadmap goals and translate technical constraints and architectural dependencies into product strategy and prioritization.
Make informed technical and product tradeoffs by understanding system architecture, engineering capabilities and business impact. Help product manager and engineering leadership navigate complex decisions.
Work closely with engineering leadership to scope work, manage technical dependencies across teams, and proactively surface and resolve blockers to support roadmap execution.
Collaborate with peer product managers to identify integration points, align on shared dependencies and ensure cohesive product delivery across multiple teams.
Enable predictable execution by helping product managers define success criteria, and proactively surface risks and tradeoffs.
Support teams throughout the product lifecycle by collaborating on release planning, launch strategy, and post launch optimization.
Communicate initiative status, risks, decisions clearly to stakeholders at all levels.

Basic Qualifications

8+ years of technical product management experience
Strong technical foundation (software, infrastructure, or systems) and ability to engage in technical discussions
Proven ability navigating complex technical initiatives with significant cross-team dependencies
Demonstrated ability to operate effectively and independently in ambiguous environments
Excellent communication
Track record of enabling the delivery of complex initiatives with high reliability and predictable outcomes

#LI-DNI

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$120,000—$160,000 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive colla