Senior Research Associate, Organic & Medicinal Chemistry

At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being proudly unique, determined to be our best, and authentic is essential to fulfilling our purpose.

The Role

We are seeking a highly motivated and skilled Senior Research Associate Organic and Medicinal Chemistry, to join our dynamic team in the Discovery Department at Genmab. As a key member of our new chemical lab, you will play an essential role in supporting the development of Antibody Drug Conjugates (ADCs) in a fast-paced and innovative biotech environment. Your hands-on expertise in organic and medicinal chemistry will be crucial in executing experiments, synthesizing compounds, and optimizing processes to advance our research and development projects.

If you are a driven and experienced technician looking to make a significant impact in a cutting-edge biotech environment, we invite you to apply for this exciting opportunity. 

Responsibilities

• Optimization and Analysis: Conduct structure-activity relationship (SAR) studies and support the optimization of lead compounds. Utilize advanced analytical techniques, including HPLC, LC-MS, and NMR, to characterize and purify compounds. 

• Laboratory Operations: Perform hands-on laboratory work, including the execution of experiments and maintenance of lab equipment. Ensure high-quality data collection and adhere to laboratory protocols and best practices. 

• Compound Design and Synthesis: Assist in the development and synthesis of novel linkers and payloads to support ADC discovery and development projects. Apply medicinal chemistry principles to assist in designing compounds with optimal pharmacological properties and ensuring effective conjugation to Genmab’s antibody formats. 

• Collaboration: Work closely with chemists and cross-functional teams, including biologists and pharmacologists, to support research projects and achieve project milestones. Contribute to the planning and execution of experiments and provide technical support as needed. 

• Innovation and Improvement: Stay informed about the latest advancements in organic synthesis and medicinal chemistry. Apply innovative approaches to problem-solving and contribute to the improvement of laboratory techniques and procedures. 

• Documentation and Reporting: Maintain accurate and detailed records of experimental procedures, results, and analyses. Assist in the preparation of scientific reports and documentation for internal use. 

• Quality and Compliance: Ensure all work is conducted in compliance with company policies, industry regulations, and safety standards. Participate in safety and compliance training as required. 

Requirements

• Educational Background: Master’s degree in Organic Chemistry, Analytical Chemistry, Medicinal Chemistry, or a related field. Relevant certifications or additional training in laboratory techniques are a plus. 

• Experience:  > 3 years of hands-on experience in organic and medicinal chemistry within a laboratory setting. Proven ability to conduct experiments, synthesize compounds, and analyze data effectively. 

• Technical Skills: Proficiency in organic sy