Director, Financial Planning & Analysis

Janux Therapeutics is seeking a Director of FP&A to serve as a strategic finance partner for clinical organization. This role will lead budgeting, forecasting, and long‑range planning while ensuring financial systems, models, and data integrity scale with the organization. The ideal candidate brings deep FP&A experience in a biotech or life sciences environment, strong systems administration experience (Adaptive preferred), and experience planning and executing clinical trials (Oncology and/or Autoimmune preferred).

ESSENTIAL FUNCTIONS AND RESPONSIBILITIES

• Lead annual operating plans, rolling forecasts, and long‑range plans for clinical functions (including Regulatory and Quality).
• Develop and maintain clinical trial budgets, enrollment‑based forecasts, and scenario models (including timeline shifts, protocol amendments, and vendor changes).
• Partner with CMO and clinical operations to monitor trial spend, burn rates, and forecasts by identifying risks, opportunities, and mitigation strategies.
• Support portfolio prioritization and investment decisions, translating clinical strategy into clear financial implications.
• Act as system owner and administrator for Adaptive Insights, including model design, data governance, integration, user access, and reporting standards.
• Build and maintain scalable financial models to support clinical programs, headcount, vendor spend, and long‑term planning.
• Partner with IT, Accounting, and FP&A stakeholders to ensure data accuracy, system controls, and audit readiness.
• Lead enhancements and continuous improvement initiatives as Janux grows, ensuring the system supports evolving business needs.
• Review and interpret PO workbooks, vendor commitments, and accrual schedules to ensure forecasts align with actual obligations.
• Help bridge FP&A forecasts with GAAP results, supporting variance analysis and management reporting.
• Present financial insights and recommendations to senior leadership in a clear, concise, and decision‑oriented manner.
• Contribute to building best‑in‑class finance processes in a fast‑growing clinical‑stage biotech environment.
• Perform other duties as deemed necessary.

EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS, AND ABILITIES

• Bachelor’s degree in Finance, Accounting, Economics, or related field.
• 8–12+ years of FP&A experience, with significant exposure to biotech, pharma, or life sciences.
• Hands‑on experience administering Adaptive Insights (or similar FP&A systems).
• Strong understanding of clinical trial budgeting, forecasting, and accrual concepts.
• Advanced Excel and financial modeling skills.
• Ability to operate effectively in a fast‑paced, evolving clinical‑stage company.
• Experience supporting oncology or clinical-stage programs is highly desirable.
• Prior accounting experience a plus.

Job Type: Full-time Benefits:·         Annual bonus program·         Incentive stock option plan·         401k plan with flat non-elective employer contribution ·         Comprehensive medical insurance with 90-100% employer-paid premiums ·         Dental and vision insurance·         HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity) ·         Unlimited PTO ·         Generous holiday schedule; includes summer and winter company shutdown ·         Relocation assistance Schedule:·         Monday to Friday Work authorization:·         United States (Required) Additional Compensation:·         Annual targeted bonus % Work Location:·         On site (San Diego, CA) EQUAL OPPORTUNITY EMPLOYER:Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.

Notice to Recruiters and Third-Party AgenciesThe Talent Acquisition team manages the recruitment and employment process for Janux. To protect the interests of all parties involved, Janux will only accept resumes from a recruiter once a fully-executed search agreemen