University of Colorado Anschutz Medical Campus

Department: Biomedical Informatics

Job Title: Laboratory Sciences Professional (Open Rank, Entry to Senior)

Position #:00844502 – Requisition #:38772

Job Summary:

The Soragni Laboratory is recruiting two full-time Laboratory Science Professionals to support research focused on patient-derived organoid models, cancer cell biology, and translational screening workflows. These roles contribute to the day-to-day execution of laboratory experiments, including organoid culture, assay preparation, and general laboratory operations.

The entry level position is intended for candidates with a Bachelor’s degree who are building foundational research experience in a translational laboratory environment.

The intermediate and senior level position is intended for candidates with prior hands-on research experience. Responsibilities across both levels may include processing primary samples, maintaining three-dimensional culture systems, supporting drug screening and characterization assays, and contributing to routine laboratory management tasks such as ordering and safety compliance. Senior-level staff will additionally support troubleshooting, workflow optimization, lab management support, independent research, and training of junior personnel.

These positions support a research program centered on patient-derived organoids, high throughput screening, and translational modeling of hard-to-treat and rare cancers-

Key Responsibilities:

• Developing, growing, and screening organoid cultures, including mini-ring organoid workflows

• Processing patient-derived and research specimens for cell culture

• Performing 2D and 3D cell culture, including assay setup and maintenance

• Assisting with assay development, including mini-ring platform drug screening

• Performing immunohistochemistry and basic cancer cell biology techniques

• Supporting flow cytometry sample prep and basic data handling

• Maintaining the Soragni Lab database, internal sample records, inventory, and consumables

• Communicate workflow updates and experimental progress clearly and reliably.

• Contribute to laboratory operations including basic safety oversight, ordering, and supply tracking.

Work Location:

Onsite – this role is expected to work onsite and is located in Auroa, CO.

Why Join Us:

At the Soragni Lab, you will join a nationally and internationally recognized translational research program focused on functional precision oncology for rare and understudied cancers. The lab integrates patient-derived organoids, high-throughput functional screening, and multi-omic profiling to directly address clinically relevant questions in sarcomas, neuroendocrine tumors, and other hard-to-model malignancies. Trainees work at the interface of experimental biology, data-driven discovery, and patient impact, generating datasets and insights that inform therapeutic strategy, biomarker development, and clinical translation within large collaborative networks.

At the Department of Biomedical