Jobs and Careers

Senior Cloud Infrastructure Engineer

Helix

United States - Remote, United StatesRemotefull_timeVerifiedPosted 8 Jun 2026

💰 $190,000/yr($148,000/yr – $190,000/yr)

About the role

Who We Are & What We Do

At Helix, our mission is simple: to help everyone improve their lives through their DNA.

Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics.

Your Career Path & Development

We are committed to your long-term growth. We invest in you through:

Cutting-Edge AI Tooling: We equip our engineers to innovate at speed. You'll have full access to GitHub Copilot, frontier models (like Claude and OpenAI), Gemini, and other new tools as they emerge, all supported by our dedicated internal AI team.
Continuous Learning: Sharpen your skills with full access to the entire Udemy learning database.
Internal Mentorship: Learn from experts across our global team through tech demos, pair programming, and collaborative projects.
Clear Advancement: We provide a framework for you to grow from one role to the next, with clear expectations and support from your manager.
Travel: Opportunities to travel to the US for collaboration with our global teams.

Your Impact in this role:

As a Senior DevOps & Infrastructure Engineer – Cloud & Automation at Helix, you will play a pivotal role in architecting, and securing our critical cloud infrastructure that supports our platform. You collaborate closely with product managers, scientists, and other engineers to innovate and evolve our cloud infrastructure while ensuring reliability, scalability, and security.

As a Senior Infrastructure Engineer – Cloud & Automation, you will:

Lead the strategic evolution of our cloud infrastructure, proactively identifying opportunities to enhance support for product teams. Drive innovation in cloud infrastructure strategy.
Collaborate with product management, scientists, and engineering teams to understand intricate requirements and develop comprehensive, forward-thinking engineering designs.
Architect and implement highly reliable and massively scalable cloud infrastructure solutions on AWS and potentially other platforms, anticipating future growth and evolving user and health system needs. Ensure alignment with the long-term architectural vision.
Champion and promote Cloud Engineering best practices across teams, influencing technical direction and standards.
Strategically lead initiatives to optimize cloud spending, demonstrating a strong understanding of budget ROI and resource utilization.
Spearhead the development and advancement of sophisticated CI/CD pipelines for highly automated, efficient, and resilient build, test, and deployment processes.
Define and implement comprehensive observability strategies, selecting and managing advanced tools to provide deep insights into system health and performance, and proactively predict and mitigate potential issues.
Mentor and guide Infrastructure Engineers by providing technical expertise, constructive feedback, coaching, and support to foster their professional development and drive excellence in cloud operations.

About You:

Experience integrating and utilizing AI-powered tools for proactive observability, cost optimization, and code analysis to improve cloud operations and development.
Ability to evaluate and recommend new AI tools to enhance cloud operations and development workflows.
A strong passion for improving people’s lives through access to better information about their DNA
Minimum of 5+ years of progressive hands-on experience in cloud architecture, deployment, and operations, demonstrating increasing technical leadership and strategic impact.
5+ years of significant software development experience in one of the following: Go, Python, or a similar language, with a proven track record of designing and implementing complex cloud-native applications and infrastructure.
5+ years of in-depth experience in cloud computing, with at least 5 years of demonstrable expert-level experience with a broad range of AWS services and a deep understanding of cloud architectural patterns.
Participate in a rotating on-call schedule, demonstrating ownership, providing leadership during incidents, and driving root cause analysis and