Senior Variant Analyst Scientist, Operations Support and Training

If you have a passion for genetics in science and the pursuit of continuous process improvements that deliver on quality and key objectives and goals, this is an ideal position for you!

Take your career to the next level as a Senior Variant Analyst Scientist - Operations Support and Training and join our growing team! This is a US Remote based position.

Position Summary:

The Senior Variant Analyst Scientist role is integral to the COST team’s operations. They contribute to a high-performing team that supports clinical operations, variant interpretation, clinical reporting, client inquiries, incident management, and process improvements across our product portfolio with a strong focus on operational efficiency. Lead the development and implementation of processes and tools to improve and scale variant interpretation and clinical reporting.

The Clinical Genomics Operations Support and Training (COST) team plays a critical role in enhancing operational efficiency and quality by centralizing the management of Standard Operating Procedures (SOPs) and reports. The team works proactively to maintain high-quality SOPs and training programs, addresses production issues, and ensures smooth case processing.
 

Candidates given the best consideration will have the following qualifications:

• Experience in a CLIA diagnostic laboratory, familiarity with next-generation sequencing, and knowledge of advanced methods of copy number detection and copy number variant interpretation

• 3+ years’ experience in variant interpretation preferred

• Experience or strong interest in operations support or training in a genetics diagnostics laboratory with a focus on operations efficiency and quality in a high volume fast paced

• Excellent verbal and written communication skills

• Experience collaborating with cross-functional teams

• Problem-solving mentality with ability to adapt plans to unforeseen challenges

• Must be self-driven and capable of working independently

• Project management experience desired

Essential Job Responsibilities:

• Critically analyze and interpret clinical and genetic information, including published literature, public and private databases, functional studies, and modeling, as well as patient clinical records

• Support clinical operations by creating or maintaining workflows for triaging, answering, and/or solving questions from the wider Clinical Genomics team

• Achieve and maintain technical and clinical competency through initial and ongoing training in a fast-paced and dynamic environment

• Receive and provide case-related and performance-related feedback in a direct and supportive setting

• Engage with Manager/Senior Manager to support team, departmental, and company objectives and key results

• Develop and maintain standard operating procedures (SOPs) and address internal and client-facing queries regarding variant interpretation and clinical reporting. As well as quality control other team’s SOPs for efficiency and consistency

• Manage incident response and provide a feedback mechanism into process improvements · Initiate and serve as directly responsible individual of projects to scale and improve clinical reporting

• Act as a scientific lead for the team and provide technical guidance across broader organization

• Manage new-hire and ongoing training programs and competency assurance protocols.

• Collaborate cross-functionally to represent Clinical Genomics in development programs with a focus on operational efficiency and quality assurance

• Drive clear decision-making and champion outcomes across the team

• Provide strategic input towards the development and refinement of tools for analyzing genetic data

• Serve as a trainer/coach to new team members

• Up to 25% of the time performing variant interpretation (aka variant curation) and report quality control using our validated in-house genetic evidence system to generate clear and concise clinical reports

Education

• PhD in biological sciences, molecular genetics, human genetics or a related field with a minimum of 3 years of relevant experience OR

• Master’s degree in Genetics or a related field, with a minimum of 5 years of relevant experience OR

• Bachelor’s degree in Genetics or a related field, with at least 8 years of related experience

Application Window open through: 04/21/2025

Pay Range: $110k-$140k annually (USD)

All job offers will be based on a candidate’s skills and prior relevant experience, applicable degrees/certificati