Senior Director, Pricing & Contracting

Zenas is a clinical-stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients with autoimmune diseases. Our core business strategy combines our experienced leadership team with a disciplined product candidate acquisition approach to identify, acquire and develop product candidates globally that we believe can provide superior clinical benefits to patients living with autoimmune diseases. Zenas is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, Zenas’ lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them. We believe that obexelimab’s unique mechanism of action and self-administered, subcutaneous injection regimen may broadly and effectively address the pathogenic role of B cell lineage in chronic autoimmune disease. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant, oral, small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with the potential to address compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Zenas’ earlier stage programs include a preclinical, potentially best-in-class, oral, IL-17AA/AF inhibitor, and a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor.

We are seeking top talent who share our commitment to patients and have a track record of success in acquiring, developing and commercializing products across the globe. Our colleagues have an opportunity to engage in a fast-paced learning environment and experience individual and organizational success as we work towards becoming a global immunology and autoimmune disease leader, while living our values of Transparency, Relationships, Urgency, Excellence and Innovation – TRUE Innovation!

Position Summary:

The Senior Director, Pricing & Contracting is responsible for developing and leading the U.S. pricing and contracting strategy to support optimal market access, reimbursement, and financial performance for Zenas BioPharma’s portfolio, including development of contracting strategies with national/regional payer organizations, PBMs, and government payer segments.  Reporting to the Vice President, U.S. Market Access, this role will lead the development of pricing strategy, gross-to-net modeling, and payer contracting strategies that support both product launch planning and lifecycle management.

The Senior Director will play a key role in establishing launch pricing strategy while also overseeing ongoing pricing governance, access financial modeling, and contracting frameworks with payer organizations, pharmacy benefit managers (PBMs), and other healthcare stakeholders. This individual will work closely with the Payer Strategy team to support contract negotiations and ensure pricing and contracting decisions align with overall market access strategy and company financial objectives.

This role will collaborate cross-functionally with Finance, Market Access, Legal, Compliance, Medical Affairs, and Commercial leadership to evaluate pricing scenarios, inform access strategy decisions, and support the successful commercialization of Zenas therapies.

This role offers a unique opportunity to shape pricing and contracting strategy in preparation for upcoming product launches while supporting long-term access and financial performance for the Zenas portfolio.

Key Responsibilities:

• Lead the development and execution of U.S. pricing strategy, including launch price recommendations and lifecycle pricing management for Zenas BioPharma’s portfolio.
• Develop and manage gross-to-net (GTN) models that support financial forecasting, access strategy decisions, and pricing scenario planning.
• Design and implement payer contracting strategies, including rebate structures and contracting frameworks with pharmacy benefit managers (PBMs), national payer organizations, and regional health plans.
• Partner with the Payer Strategy team to support contract negotiations and ensure pricing and rebate strategies align with payer coverage objectives.
• Lead financial modeling and pricing scenario analyses to evaluate the impact of pricing and contracting strategies on market access, reimbursement, and overall company financial performance.
• Collaborate closely with Finance to ensure pricing assumptions, GTN forecasts, and contracting scenarios are accurately reflected in financial planning and forecasting models.
• Monitor competitive pricing dynamics, payer contracting trends, and reimbursement environments to inform pricing strategy and market access planning.
• Support the developme