Clinical Research Coordinator I

The Brain and Data Sciences Lab is known for using multiple types of genomic data to dissect the clinical features of schizophrenia and bipolar disorder, developing a novel framework for human brain research with the Living Brain Project, and advocating for the rapid translation of genomic findings to early-phase clinical trials of experimental therapeutics.

To understand the human brain, scientists use clinical observation, neuropharmacology, neuroimaging, neurophysiology, neuromodulation, and molecular-cellular neuroscience. However, applications of molecular-cellular neuroscience have traditionally been limited to post-mortem specimens or cultured neural cells, whereas the other approaches require interactive living subjects. As a result, it is rare that a single cohort is studied using the full human subject neuroscience toolkit. The biological foundations of neuropsychiatric traits therefore remain largely unknown and understanding the inner workings of the human brain continues to be one of the greatest scientific challenges.

The Living Brain Project is a multiscale, data-driven investigation of the human brain wherein a single living population is being studied using all the tools available for human-subject neuroscience. Led by Drs. Alexander Charney and Brian Kopell, this study will enroll 500 men and women from young to old age receiving deep brain stimulation (DBS) over a 10-year period. Batteries of neuropsychological testing will survey all domains of cognition and mental health, while electronic medical records will create a high-resolution digital record of the health of each participant. Brain structure and function will be recorded through multi-modal neuroimaging, and during each of two DBS electrode implantation surgeries (one per hemisphere) specimens will be obtained from the participant’s brain, skin, and blood for cutting-edge multiomic analyses. With this unique cohort, the Living Brain Project aims to discover how interactions between the various levels of neurobiology, neurophysiology and neuroanatomy assessed give rise not only to the chronic traits that have been probed in post-mortem studies (e.g., depression, dementia), but also acute states that can only be assessed in a living cohort (e.g., sadness, working memory).

The Clinical Research Coordinator I will participate in clinical research activities related to the Living Brain Project. The Clinical Research Coordinator I will be responsible for obtaining informed consent as well as collecting, maintaining, and organizing study information. They will also be responsible for collecting biospecimen from consented patients when they are undergoing DBS and deliver the samples to the lab for processing. They will also assist in preparing documents (for e.g., Institutional Review Board, Grants and Contracts Office) and performing other study related activities as needed. 

The ideal candidate will have the following experience:

• Background in clinical research or closely related field
• Strong communication and organization skills
• Passion for patient care and clinical research 

Primary responsibilities include:

• Obtain informed consent and educate participants regarding study requirements.
• Collect and record study data and input all information into a database.
• Assist in activities related to clinical research studies including but not limited to answering phone calls, screening participants for eligibility, scheduling/coordinating specimen drop off.
• Assist in IRB/GCO applications as needed. 
• Maintain source documents and subject files in accordance with hospital procedures. Ensure accurate and complete compilation of subject data through chart reviews. 
• Collect, process, deliver and ship clinical specimens as required by the protocol. 
• Perform other related duties as requested.

• Bachelor’s degree in life sciences or related field
• Proficiency in Microsoft Office Suite 
• Demonstrated ability to work effectively, communicate clearly, and accomplish goals 
• Pristine attention to detail and ability to manage time appropriately, able to multitask in a fast-paced environment 
• Effective interpersonal skills, able to establish good working relationships and collaborate with networks of employees at all levels, able to foster cooperation in others 

Compensation Statement

The Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for this role is $58,661.00 - $83,000.13 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or