Senior Director, Commercial Supply Chain

Job Description

This Senior Director Commercial Supply Chain will be responsible for leading supply chain commercial readiness for a late-stage biologic program.  Vertex is rapidly expanding the portfolio and commercializing a pipeline of exciting new therapies. We are growing our capabilities to support the biologics commercial supply chain and manufacturing of these therapies. This role will be responsible for leading the biologics global supply chain including strategy and launch operations. This strategy includes manufacturing network decisions in partnership with External Manufacturing and commercial supply requirements including 3-5 year material, capacity and equipment requirements. This role will also be responsible for integrating across the supply chain logistics and systems organizations to deliver a best-in-class supply chain. The Senior Director has interaction and impact across multiple Vertex departments and will represent the broader BSMO organization in several cross-functional forums. The Senior Director will cultivate multiple cross-functional business relationships to deliver a robust supply chain strategy and reliable operations for patients.  

This role will report to the VP of Supply Chain Management within the Biopharmaceutical Sciences and Manufacturing Operations (BSMO) division. This supply chain leadership position will be responsible for identifying future capabilities required and building out a high performing, diverse team focusing on developing and implementing a robust biologics supply chain. The position is based at Vertex’s corporate headquarters in Boston, MA.   

Key Responsibilities:     

• Establish the commercial supply chain strategy for biologic programs including network strategy, scenario planning for future launches and partnering with Systems to advance technology and enable data driven decisions. This strategy includes launch supply and a 3-5+ year forward looking assessment of commercial forecast scenarios, material build plans and a complex technical agenda to deliver an integrated, best-in-class supply chain.      

• Leadership of global Sales & Operations Planning process to enable robust material and capacity investments including expansion across CDMO network. Partner with Finance and Commercial colleagues to deliver a plan including balancing forecast scenarios, risk and budget impact. Present recommendations and rationale in Sr. Leader forums.  

• Define a strategic material build plan across raw materials through finished goods taking into consideration supplier capacity, demand uncertainty and overall risk management.   

• Responsible for proactively assessing risk across the biologics supply chain and building mitigation plans.   This includes a forward-looking approach to future supply chain risks and developing options for risk mitigation and business continuity.   

• Deliver an integrated supply chain launch plan for a late-stage program. This strategy includes establishing safety stock for raw materials, CDMO operational readiness to successfully launch, capacity analysis and integration of systems requirements and complicated short-lead time cold chain logistics.  The Executi