Senior Director, Head of Precision Medicine GI and CRC tumours

Job Title: Senior Director, Head of Precision Medicine GI and CRC Tumours

Location: Gaithersburg, MD

Introduction to role

Are you ready to lead and shape the future of precision medicine in gastrointestinal (GI) and colorectal cancer (CRC) tumours? As the Senior Director, Head of Precision Medicine GI and CRC Tumours, you will be at the forefront of developing and implementing global Precision Medicine and Diagnostics Development Strategies. You will oversee the precision medicine or Companion Diagnostics plans, ensuring their successful delivery for portfolio programs and clinical studies within the GI and CRC tumour areas.

Join us in making a significant impact on patient outcomes by aligning these strategies with our overall tumour strategy.
 

Accountabilities

As a key member of the Tumour Council or strategy team, you will represent the Precision Medicine and Biosamples (PMB) function, supporting and shaping the tumour strategy and respective drug portfolio. You will lead Diagnostic Subteams, ensuring the successful delivery of companion diagnostic and precision medicine strategies for the associated group of portfolio assets within the GI and CRC tumour areas. Your responsibilities will include:

• Leading and shaping the global Precision Medicine and Diagnostics Development Strategy for GI and CRC tumours.

• Providing high-quality scientific advice on strategic direction for precision medicine approaches and diagnostic development.

• Ensuring the adoption of precision medicine strategies within Oncology R&D and the Oncology Business Unit.

• Driving forward, accelerating, and innovating Precision Medicine approaches in the GI and CRC tumour areas.

• Leading strategic investments to enable oncology companion diagnostic development.

• Shaping the external environment to address barriers and facilitate diagnostic development relevant to the therapeutic area.

• Overseeing global cross-functional teams across PMB and other global functions.

• Contributing to transformative development and strategic investment that impacts Oncology R&D’s registrational drug portfolio.

• Ensuring world-class practice in Precision Medicine approaches and Companion Diagnostic developments.

• Providing input to the global PMB strategy and leading technical advice in specific areas of expertise.

• Collaborating with drug co-development external diagnostic partners to align strategies.
   

Essential Skills/Experience

• PhD or equivalent experience in a relevant subject

• Proven delivery of Precision Medicine strategies and Companion Diagnostic tests through regulatory submission and launch, within a diagnostic or pharmaceutical setting

• Substantial scientific and business experience of Precision Medicine and diagnostic development approaches within the relevant therapeutic area or tumour area

• Proven strategic capability innovation and putting strategy in action

• Broad understanding of CDx regulations in US, EU, Japan, and China and proven global regulatory interactions

• Substantial (7+ years) experience in drug development, diagnostic development, and regulatory interactions

• Evidence of excellent skills in communication, stakeholder management, influencing, and program management

Desirable Skills/Experience

• Significant previous experience in a similar role in different companies

• Delivery of multiple examples of companion diagnostics, regulatory interactions (particularly with FDA), and commercialization

• High-quality scientific expertise in the precision medicine field relevant to the therapeutic area as evidenced by publications and external reputation

• Evidence of shaping the companion diagnostic field e.g., diagnostic partnering, regulation of drugs and linked diagnostics, payer and policy considerations, ethical and legal aspects

• Led Precision Medicine strategic initiatives in similar roles
   

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
 

At AstraZeneca, we are committed to making a difference by following the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of th