Post-Doctoral Research Fellow- Medical Oncology- Lab of Dr. Claudia Capparelli

Job Details

We are seeking a Postdoctoral Fellow to join our research program to investigate the mechanisms underlying tumor heterogeneity and plasticity in melanoma with the goal of identifying novel treatment strategies for melanoma patients. Our research aims to identify and target pathway dependencies and vulnerabilities in drug tolerant persister cells in order to prevent metastasis and improve treatment options for melanoma patients.

Job Description

Additional research interests include: i) characterizing alterations that occur in the Extra Cellular Matrix during the establishment of drug tolerance and ii) investigate therapies that mediate changes within the tumor immune microenvironment as an approach to improve response to immunotherapies. Understanding alterations in the tumor microenvironment could ultimately lead to the identification of novel therapeutic approaches for the treatment of melanoma. Our research ranges from fundamental molecular mechanisms to clinical applications utilizing molecular and cellular biology, 3D cell culture, flow cytometry, omics studies, and mouse models. 

A Ph.D. or equivalent is required

Work Shift

Workday Day (United States of America)

Worker Sub Type

Regular

Primary Location Address

951 Locust Street, Philadelphia, Pennsylvania, United States of America

Nationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research. Thomas Jefferson University, home of Sidney Kimmel Medical College, Jefferson College of Nursing, and the Kanbar College of Design, Engineering and Commerce, dates back to 1824 and today comprises 10 colleges and three schools offering 200+ undergraduate and graduate programs to more than 8,300 students. Jefferson Health, nationally ranked as one of the top 15 not-for-profit health care systems in the country and the largest provider in the Philadelphia and Lehigh Valley areas, serves patients through millions of encounters each year at 32 hospitals campuses and more than 700 outpatient and urgent care locations throughout the regi