Vertex Pharmaceuticals-Clinical Science Postdoctoral Research Fellow

About the Opportunity

About the Opportunity

Northeastern University Pharmaceutical Industry Fellowships Program is a two-year experiential program designed to advance lifelong learning and the education and training of Pharm.D. graduates. A key element of the program’s success is preparing Fellows to meet evolving workforce needs across various sectors of the pharmaceutical industry.

Fellows have the opportunity to work closely with our innovative biopharmaceutical industry partners, while engaging with Northeastern University faculty in professional and career development, teaching, service, and scholarly activities.

In partnership with Northeastern University, Vertex Pharmaceutical is offering a two-year Clinical Science fellowship, based in Boston, Massachusetts.

About Vertex

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia and acute pain, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy, primary membranous, nephropathy, autosomal dominant polycystic kidney disease, type 1 diabetes, and myotonic dystrophy type 1.

Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 15 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube and X.

Clinical Scientist Position Description:

The Clinical Scientist fellow will act as a key clinical interface with the Medical Lead to provide scientific, clinical, and operational input contributing to the clinical development programs at Vertex, working on cross-functional study teams for the design, execution, and monitoring of clinical trials, as well as assisting with data interpretation and communication. This role will also serve as a point of contact for external collaborations with clinical investigators and thought leaders. The Clinical Scientist fellow will learn various aspects of the drug development process, while focusing on specified deliverables for a specific program. Activities will include program team involvements and presentation skills development. In addition, the fellow will have the opportunity to interact with, and learn from, other groups at Vertex with an aim of providing a broader understanding of Clinical Research.

Responsibilities

·       Work with cross-functional teams as the clinical representative and liaison to the therapeutic area to conduct clinical studies, including study start-up, safety and medical monitoring, and study close-out activities

·       Support Medical Lead with medical monitoring reports, safety reviews, site interactions, and reviewing tables, figures, and listings (TFLs). Responsible for analytical support of clinical trial data (safety and efficacy), including gathering, analyzing, reviewing, interpreting, and providing preliminary assessments and recommendations to the Medical Lead. Analyze and synthesize information to assess issues relating to protocol conduct and/or individual subject safety. Assist in communicating a clear overview of trial results

·       Provide support for Data Monitoring Committees including operationalizing the charter, preparing updates and blinded data reviews, execution of meetings and adjudications, and communication of synthesized data reports

·       Contribute to protocols, clinical study reports, Investigator’s Brochures (IBs), informed consent forms (ICFs), manuals, training documents, and other clinical documents under the direction of the Medical Lead

·       Lead interactions with internal and external stakeholders (study sites, vendors, committees, etc.) in support of clinical trial objectives

·       Contribute to the organization, preparation, and execution of investig