Senior Medical Physicist

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

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RayzeBio (a Brystol Myers Squibb Company) is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals

The Senior Medical Physicist will be responsible for applying their expertise in radiation physics to the research and development of new drugs and therapies. Their focus will be on radiopharmaceuticals and analyzing data from in vitro and vivo studies as well as clinical diagnostic and therapeutic studies. The candidate will be responsible for designing and leading clinical image-based dosimetry analysis including the optimization of imaging protocols for quantification and implementation in clinical studies globally. The candidate will be responsible for all aspects of clinical dosimetry calculations and lead strategic discussions on dose determination working closely with internal stakeholders as well as external vendors and experts. 

Job Responsibilities:

Essential duties and responsibilities include the following. Other duties may be assigned.

• Work  closely with the Radiation Biophysics leading all aspects of internal dosimetry analysis in the clinical development of radiopharmaceutical imaging and therapeutic agents.

• Develop clinical dosimetry analysis plans and conduct or oversee plan execution.

• Establish dosimetry vendor selection criteria, including evaluating commercialized and research dosimetry software.

• Work closely with the nuclear medicine physician in analyzing data from imaging modalities like PET (positron emission tomography) and SPECT (single-photon emission computed tomography) to assess drug uptake and distribution,

• Review imaging protocols for clinical studies, with a focus on the optimization of acquisition and reconstruction parameters for quantitative imaging

• Identify and determine best practices and standardization processes for image data quality control in clinical research, aligned with guidelines from global regulatory organizations

• Lead dosimetry discussion in cross-functional teams  to contribute to the design of radiopharmaceutical clinical trials, , including patient dosimetry calculations and quality control procedures.

•  Analyze clinical imaging data to assess treatment response and identify potential toxicities associated with radiation

• Ensure compliance with regulatory requirements and prepare documentation for regulatory submissions

• Explore new technologies and approaches to improve the development of radiopharmaceuticals, such as novel radioisotopes or targeted delivery systems.

• Contribute to the advancement of medical physics knowledge in the field of radiopharmaceuticals and represent RayzeBio externally as a leader in RPT.

• Provide strategic expertise, technical support, training and problem-solving solutions to cross-functional teams as needed.

Basic Qualifications:

• Advanced degree in  Medical Physics or a related field with didactic training in internal dosimetry.

• Minimum of 7 years of experience in molecular imaging and internal dosimetry clinical research

• Minimum of 2 years experience in pharma or biotech industry in a cross-functional matrix environment required

Preferred Qualifications:

• PhD

• Experience with radiopharmaceuticals as