Associate Director, ADC Target Validation, Oncology R&D

Associate Director, ADC Target Validation, Oncology R&D

Gaithersburg, MD

Are you ready to make a difference in the world of Oncology? We are seeking an Associate Director in Tumor Targeted Delivery (TTD) to develop a comprehensive strategy to validate new targets for ADCs, understand the role of targets in cancer biology and support novel ADC platform and project development. This is your chance to be at the forefront of Oncology R&D, working in partnership with the TTD team across the globe, leading the implementation of novel target biology validation efforts.

Accountabilities:

As an Associate Director, you will lead a team focused on validation and early pipeline progression of potential ADC targets. You will collaborate with internal teams to prioritize targets, develop validation strategies, and prepare project packages for milestone transitions in the early ADC and RC portfolio. Your role will also involve supporting project teams with requests for tools and reagents for later portfolio projects. You will lead internal and external research collaborations supporting target validation and discovery efforts. Lastly, you will lead efforts to continue to refine target selection and ADC development strategies, such as understanding the contribution of target engagement, internalization and payload release.

Essential Skills/Experience:

• PhD in relevant field and at least 3 yrs related experience
• Proven leadership skills
• Experience in validation and early pipeline progression of potential ADC targets
• Ability to collaborate with internal teams to prioritize targets
• Experience in developing validation strategies
• Ability to prepare project packages for milestone transitions in the early ADC and RC portfolio
• Experience in supporting project teams with requests for tools and reagents for later portfolio projects
• Proven track record of leading internal and external research collaborations supporting target validation and discovery efforts
• Experience in refining target selection and ADC development strategies

Desirable Skills/Experience:

• Experience in ADCs with different types of antibody formats, linker-payloads and conjugation chemistries

At AstraZeneca, we are on a mission to eliminate cancer as a cause of death. We are a science-based, leading and decisive Oncology enterprise united in our vision. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. Our pipeline is a testament to our growth, both now and in the future.

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

Ready to make a meaningful difference? Apply now and join us in our mission to eliminate cancer as a cause of death!

If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: July 9, 2024

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more?

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