University of Colorado Anschutz Medical Campus

Department of Pediatrics | Section of Genetics & Metabolism

Job Title: Open Rank Laboratory Sciences Professional

Position #: 00843592 – Requisition #:38593

Job Summary:

A full-time (1.0 FTE) Laboratory Sciences Professional (Entry or Intermediate) position is available in the field of genomic mosaicism. The research group is located within the Department of Pediatrics, School of Medicine, in the Section of Clinical Genetics and Metabolism. This position will be responsible for performing a broad array of genetic and molecular assays and techniques in the area of genetics, genomics, and molecular biology. This work will be part of essential laboratory support tasks and include experiments performed independently and under the supervision of the principal investigator and other laboratory members. In addition, this position will be responsible for managerial aspects of the Breuss laboratory, support of the Principal Investigator’s (PI) scientific administration (all levels), and the mentoring of junior researchers (Intermediate only).

Key Responsibilities:

The duties and responsibilities of the position include, but are not limited to:

Laboratory Tasks

• DNA/RNA preparation from primary human tissues (e.g., blood, saliva, semen, postmortem or surgical tissues), primary cells, or immortalized cell lines.

• Standard and advanced molecular biology and genetic techniques, such as molecular cloning, PCR, ddPCR, library preparations, and analytical methods (e.g., gel electrophoresis).

• Maintenance and experimentation in cell culture systems, including expansion of cell lines, cryopreservation, and routine mycoplasma testing.

• Maintaining a detailed, accurate, and current experimental record.

• Data organization and analysis.

• Active participation in laboratory meetings and journal clubs.

• Drive projects independently (Intermediate only).

Laboratory Management

• Manage daily laboratory operations: ordering and maintaining inventory, keeping organization and cleanliness of equipment and working spaces, preparing reagents, maintaining laboratory records and databases, and ensuring safety and regulatory compliance of the laboratory.

• Assist in the review and implementation of lab support policies, practices, and programs to meet organizational, operational, and management needs.

• Processing, storage, and tracking of biological specimens.

• Coordinate and execute shipping and receiving of biological specimen sampling kits.

• Develop, maintain, and revise standard operating proc