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Clinical Laboratory Scientist (CLS), Prenatal

BillionToOne
United Statesfull_timeVerifiedPosted 17 Mar 2026
💰 $200,536/yr($173,940/yr$200,536/yr)

About the role

Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

With over 700 employees, half a million patients helped, and one of the most successful IPOs in medical diagnostics history behind us, we're just getting started. Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for driven Clinical Laboratory Scientists (with California Clinical Laboratory Scientist License) to perform UNITY, the only non-invasive prenatal test (NIPT) that can detect inherited disorders such as sickle cell disease, spinal muscular atrophy, and cystic fibrosis in the baby directly from maternal blood. These disorders are extremely severe, but early detection and intervention can significantly improve outcomes. You will join our growing superstar CLIA team responsible for end-to-end processing of pregnancy blood samples in a high complexity, high-growth CLIA setting. The Clinical Laboratory Scientist is an onsite position.

Shift Hours: Tues-Sat AM / Tues-Sat PM 

  • Weekday PM, 20% differential
  • Weekend PM, 25% differential

Austin Expansion Update:
We are building a brand-new state-of-the-art laboratory in Austin, Texas, expected to launch in late 2027 / early 2028, and we are looking for talented laboratory professionals who want to be part of this journey from the very beginning.

Candidates hired into this role will initially relocate to the Bay Area (Union City, CA) to train and work alongside our experienced laboratory teams. During this time (up to ~18 months), you will gain deep hands-on experience with BillionToOne’s cutting-edge molecular diagnostic workflows, quality systems, and laboratory operations before transitioning to our new Austin facility once it opens.

This is a unique opportunity to gain hands-on training with our experienced lab teams and become one of the founding members of our Austin laboratory.

Responsibilities:

  • Performs clinical laboratory assays to provide data for diagnosis, treatment, and prevention of disease.
  • Performs quality control studies to ensure the accuracy of clinical data.
  • Verifies instrument performance by checking and calibrating specific lab instruments and documents data.
  • Organizes and contributes to R&D to CLIA tech transfer and troubleshooting, training, and validations

Qualifications:

  • Bachelor's degree in the chemical, physical or biological sciences
  • 1-2 years of CLS experience in a clinical setting
  • A current California Clinical Laboratory Scientist License that meets requirements for Testing Personnel under CLIA regulations (42 CFR, part 493) (ASCP, CGMBS or generalist license is required).
  • Hands-on training and experience with manual molecular biology protocols, including DNA extraction and PCR
  • Advanced knowledge of Google Docs, Word, Excel, basic statistics and familiarity with LIMS systems
  • Strong attention to detail and ability to work flexibly and well under given timeframes.
  • Self-starter and dynamic team player with excellent verbal and written skills.

Nice-To-Haves:

  • Start-up experience
  • Knowledge of medical genetics
  • Experience in a cell-free DNA setting

Benefits And Perks:

  • Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
  • Open, transparent culture that includes weekly Town Hall meetings
  • The ability to indirectly or directly change the lives of hundreds of thousands patients
  • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
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Company

BillionToOne

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