Senior Scientist, Analytical Chemistry and Purification

Job Description

Our company SSF has a position open for a High-Throughput Purification (HTP) Senior Scientist within the Discovery Chemistry Department located at our South San Francisco, CA site.  The successful candidate will be highly independent and detail-oriented, with an analytical mindset and thrives in a fast-paced, collaborative team environment.  The candidate will be responsible for developing chromatographic methods and provide routine and specialized purification support and reporting for a range of modalities at varying scales, leveraging a variety of analytical techniques, novel instrumentation, and custom informatics tools.  Specific responsibilities will include:

Job Responsibilities: 

• Be an integral part of our company's growing High-Throughput Purification team and work with chemists, biologists, and engineers to advance our drug discovery pipeline

• Operate state of the art analytical and purification instrumentation (HPLC, UPLC, SFC, Hi-Res MS, 2D-LC) to characterize and purify lead candidates from small molecules to peptides and bioconjugates

• Proactively develop specialty separations, and optimize related chromatographic methods for individual programs

• Help identify, evaluate, and recommend novel instrumentation and workflows to achieve early-stage project goals

• Collaborate with automation teams to design and implement machine learning software tools and robotics to automate laboratory workflows and processes

• Oversee overall instrument performance and health, perform basic troubleshooting, and schedule preventative maintenance and repair with key vendors

• Contribute to our external scientific presence through presentations and the writing of technical documents, scientific manuscripts, etc.

Qualifications: 

Education:

• Bachelor's (with 7+ years), Master's (with 4+ years) or Ph.D. in Analytical Chemistry, Chemical Engineering, Biochemistry or related field with relevant experience listed below

Required Experience and Skills:

• Hands-on research experience in a pharmaceutical/biotech setting and familiarity with Waters, ThermoFisher, and/or Agilent LC-MS instrumentation, relevant software platforms, subsequent data analyses and interpretation

• Demonstrated ability to independently develop and perform critical experiments in a fast-paced, dynamic environment

• Self-motivated with high attention to detail, ability to rapidly analyze, summarize and present data and significant conclusions

• Excellent organizational skills with ability to meet deadlines and prioritize work on multiple projects

• Uncompromising integrity and proven success working in a high-performing, diverse, and inclusive team environment

• Ability to communicate clearly and build collaborative relationships is essential

Preferred Experience and Skills:

• Data science and/or computer programming experience with knowledge of AI/ML software tools for predictive analytics to improve decision-making

• Prior exposure to high-throughput lab operations, automation, and compound array purification

#EligibleforERP 

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

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