Senior Laboratory Scientist

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

The mission of the Innovation Lab is to increase the diagnostic yield of our exome and genome products and reduce the time to diagnosis for patients with undiagnosed hereditary disease. Our vision is to deliver personalized and actionable health insights to every person who orders a genetic test from GeneDx. Achievement of our goals will require a culture of innovation, where creativity, experimentation, and the pursuit of new ideas are encouraged and embraced. Individuals are empowered to think critically, take risks, and challenge the status quo, to generate breakthrough solutions and drive positive change.

Summary:

We are seeking a highly skilled and experienced Senior Laboratory Scientist to join our Research and Innovation team, focusing on new assay design and development. The ideal candidate will have a strong background in laboratory science, assay development, and a proven track record of driving innovative research projects. This role involves leading the design, optimization, and validation of assays, as well as collaborating with cross-functional teams to advance our scientific and product development goals.

Responsibilities:

• Lead the design, development, and optimization of novel assays for various diagnostic applications, ensuring high sensitivity, specificity, and reproducibility.
• Manage and execute R&D projects from conception to completion, ensuring timely delivery, and high-quality results.
• Analyze experimental data, interpret results, and provide actionable insights to guide research directions and product development.
• Work closely with biologists, chemists, engineers, and other scientists to design experiments, troubleshoot issues, and achieve project milestones.
• Maintain detailed and accurate records of experimental procedures, results, and conclusions.
• Prepare technical reports, presentations, and publications.
• Implement and maintain quality control procedures to ensure the reliability and accuracy of assay results.
• Provide guidance and mentorship to junior scientists and laboratory technicians, fostering a collaborative and innovative research environment.
• Ensure all laboratory activities comply with relevant regulatory requirements and industry standards.

Education, Experience, and Skills:

• Ph.D. in Biochemistry, Molecular Biology, Analytical Chemistry, or a related field.
• Minimum of 5 years of postdoctoral or industry experience in assay development and laboratory research.
• Proficiency in NGS techniques, including DNA/RNA extraction, library preparation, DNA/RNA sequencing using short-read and/or long-read sequencing technologies.
• Experience with high-throughput sequencing and automation.
• Strong understanding of statistical methods and data analysis software.
• Familiarity with laboratory information management systems (LIMS) and electronic lab notebooks (ELNs).
• Demonstrated ability to analyze complex experimental data and derive actionable insights.
• Excellent written and verbal communication skills, with the ability to present complex information clearly and concisely.
• Proven ability to work effectively in a collaborative, multidisciplinary environment.

Physical Demands:

• Ability to stand, walk, and sit for extended periods.

Work Environment:

• Onsite in Gaithersburg Laboratory.
• Work is primarily performed in an office setting with a typical climate-controlled environment.
• Occasional exposure to manufacturing or warehouse areas, which may involve loud noises, dust, and varying temperatures.
• The role may require occasional travel to client sites, with potential exposure to outdoor weather conditions.

 

Pay Transparency, Budgeted Range$153,053—$191,317 USD

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Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitm