Global Head of Digital Biologics Platform, Large Molecule Research Platform (LMRP)

Job title: Global Head of Digital Biologics Platform, Large Molecule Research Platform (LMRP)

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress.

The Global Head of Digital Biologics Platform in the Global Large Molecules Research Platform (LMRP) will be responsible for establishing and implementing the strategy for LMRP related to all digital and computational approaches for our discovery and engineering workflows.  She/he will also be a key contributor to the platform’s long-term strategy for sustainable and innovative biologics.  Digital applications are central to our innovation approach and to the advancement of our biologics strategy.  Our digital strategy begins with the core foundational approach to our data governance and includes advanced initiatives in Machine Learning and Artificial intelligence to improve our workflows and increase our ability to deliver first in class and best in class biologic drugs to the market.  LMRP is a large global organization responsible for generating the biologic compounds entering the Sanofi pipeline.  This organization consists of sites within Cambridge, MA (US); Vitry, France; Frankfurt, Germany; Ghent, Belgium; and Cambridge, UK. The Global Head of Digital Biologics Platform will directly manage a team in the five countries in which LMRP operates and will be responsible for working with key collaborators across Sanofi including all functions within Research, and Digital and Operations to advance the digital strategy for the LMRP organization.  The Global Head of Digital Biologics Platform will co-lead external strategic partnerships and ensure success of the collaborations.  As a member of the LMRP leadership team, the Global Head of Digital Biologics Platform will manage the foundational digital approaches at all LMRP sites, set the LMR Digital AI innovation goals and targets, and execute on these.  This role will report to the Head of Global Large Molecule Research Platform and is expected to have a strong impact on the platform’s portfolio and performance.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities:

• Defining and executing on LMRP’s data, digital and AI near-, mid-, long-term strategy in support of Sanofi’s overall business strategy

• Building of next generation AI-driven biologics discovery and design pipelines together with Digital and global LMRP consisting of the computational engine and requisite laboratory platform and automation technologies

• Establishing and implementing data governance and acquisition practices across LMR with the support of an imbedded direct report at each LMR site, in collaboration with the R&D Data Office

• Developing the framework for foundational data exploitation: the base capabilities for exploiting data across LMR, including data and infrastructure for sustaining future advanced applications.  This includes provisioning of tools, advocating for appropriate infrastructure and working with the LMR global organization on building expertise to expand use of data for daily decision making and operations, for monitoring platform performance, and for performing specific computational biology-related functions (e.g. structure prediction/modeling, predictive modeling and data-mining for discovery and drug design)

• Defining and implementing AI method validation, acceptance and operationalization processes with the goal of maintaining rigor in the practice of drug discovery, applying AI efficiently, and on applications with the most value

• Co-managing data and ML operations together with Digital team to ensure state of the art computational platforms (e.g. enabling automated monitoring and update of predictive models with newly accumulated data)

• Leading the DBx (Digital Biologics) group which consists of a matrix organization of scientists across global LMR that are executing on digital initiatives across the spectrum from foundational to advanced AI applications

• Overseeing change management within the LMRP organization as it undergoes digital and AI transformation, including defining new Ways of Working and workforce upskilling

• Computational platform innovation: development of new or extension of computational platforms, as complement or alterna