Senior Expert I Data Science (Translational Medicine)

Band

Level 4

 

Job Description Summary

#LI-Hybrid

This role will be located at our Cambridge, MA site and cannot be located remotely.

We work at the cutting-edge of data science and transformative medicine, shaping the future of clinical drug development. Our passion for multivariate data modeling and AI/ML techniques is only surpassed by our desire to improve the lives of patients. Our scientific reasoning, clear communication, and desire to learn are as essential to finding solutions as our agility with diverse data types. We are Data Scientists in Translational Medicine. Are you ready to reimagine medicine with us?

As a member of the Quantitative Sciences & Innovation (QSI) unit in Biomarker Development, you will join Novartis’ clinical trial teams to speed new medicines into the clinic across one of the industry’s largest and most innovative portfolios. By integrating high-throughput biomarker technologies from First-In-Human through Phase III clinical trials, you will investigate disease heterogeneity, drug efficacy, and patient safety at molecular resolution to advance trials in new indications and patient populations. You are passionate and curious scientist, eager to bring creative solutions to biology’s most daunting challenges on our journey to reimagine medicine. Working alongside dedicated physicians and biomarker scientists, our Data Scientists provide the analytical insights that drive Translational success.

 

Job Description

Key Responsibilities:

• Conceive, design, and execute exploratory analyses as Lead Data Scientist across First In Human, Phase I-III clinical trials, applying advanced analytical methods as required

• Participate in and lead cross-functional biomarker collaborations with partners across the Research-Development-Commercial continuum to support target selection and registration activities

• Provide subject matter expertise for high-dimensional clinical data and analysis solutions to inform patient stratification and enrichment strategies

• Work expeditiously as a member of matrixed clinical trial teams with diverse membership and expertise

• Contribute data analyses and subject matter expertise to Biomedical Research/Translational Medicine (BR/TM) level workstreams, including Translational Data Science SteerCo and cluster activities, focusing on genetics, genomics, proteomics and related data

Essential Requirements:

· PhD in statistical genetics, bioinformatics, biostatistics, computational biology, data science, or a related quantitative field

· 2+ years of experience analyzing large-scale, high-dimensional biological datasets in drug discovery, clinical development, or a translational research setting (industry or academic) or 4+ years of exemplary research in a field of equivalent complexity)

· Proficiency in statistical programming using R and/or Python, with a strong foundation in reproducible research practices

· Experience in real-world evidence (RWE) and biobank-scale data mining, including the ability to extract, integrate and analyze complex data sources to support translational research and clinical development

· Deep expertise in at least one of the following areas, with a demonstrated ability to learn and apply the other:

· Human genetics and molecular epidemiology, including analysis of genomic, proteomic, and/or metabolomic data e.g. GWAS, PRS, MR and xQTL

· Statistical and machine learning methods, such as longitudinal modeling, signal processing, causal inference, or high-dimensional data integration

· Proven ability to communicate complex analytical concepts clearly and effectively to interdisciplinary teams, including clinicians, biologists, and regulatory stakeholders

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The salary for this position is expected to range between $119,700 and $222,300 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

 

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in