Sr. Director - Radioligand Therapy Operations

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Role Description:

This position is responsible for the overall supervision of manufacturing operations for the commercial and clinical production of radioligand therapies.  The Senior Director Operations is directly responsible for managing the manufacturing operations function and ensuring it has the necessary capacity, capability and leadership structures in place to deliver the site manufacturing plan. The role is also responsible for leading the integration of the cross-functional management team that provides functional support to manufacturing operations.  This role will be key to ensuring a strong safety culture and establishing a safety focused mindset within the organization.

The Senior Director Operations is also a member of the Lilly Indy RLT Site Lead Team, that has collective responsibility to develop and implement the strategic direction, organizational capability and management of the site.  Primarily, the members of the team drive the site toward achieving long term business objectives; they continuously develop the business and the organization for the future bearing in mind corporate objectives and the continuously changing external environment; and they manage issues that span multiple teams in the organization and extend into the broader corporate/external context.  

In the pre-commercial phase (commercial operations expected mid-2026), the Site Lead Team roles will be fluid and dynamic as we endeavor to support commercial launch readiness activities, site growth and continued build out, integration of the site into the Lilly M&Q organization and build out of site culture. This will require significant collaboration, creativity and resilience as the site launches commercial GMP manufacturing operations.

Key Responsibilities for this role include: 

Pre-Commercial Launch Phase: 

• Be a collaborative, inclusive, energetic leader and support the broader lead team to: 

• Build the organization with the necessary capability, capacity and culture to operate this facility to the highest standards of safety, quality, and operational excellence. 
• Develop and implement the systems and processes needed to run the site, leveraging existing Lilly knowledge where necessary, but also incorporating external experiences and learning.   
• Establish lean practices and a continuous improvement mindset throughout operations and the direct supporting organizations.   
• Establish an operational shift structure and team to support manufacturing of RLTs 5 days per week. Incorporate efficiencies and strive to improve workflows to create a lean, effective operation.

Post Commercial Launch:  

• Develop and deliver the production plan for the site in alignment with the global supply chain group.
• Ensure compliance to batch release and shipping schedules.
• Lead continuous improvement projects through capacity optimization and cost reduction programs.

• Develop the strategic and operational plans for Production Operations and be responsible for the execution of these plans.

• Participate in development and delivery of the medium and long term strategic direction for the site.  

• Ensure Manufacturing Operations remain compliant with all applicable regulatory requirements. (e.g. Safety, Quality/cGMP, Environmental, Financial, Legal, HR.)  

• Ensure Process Teams meet expectations described in Lilly’s Manufacturing Standards for Operational Excellence.

• Ensure that a robust control system exists to manage the business, identify compliance issues and escalate issues appropriately.
• Review site and Busines