Executive Medical Director, Global Medical (Nephrology)

Job Description

General Summary:

The Executive Medical Director, Global Medical Lead (GML), Nephrology is a critical leadership role in Global Medical, responsible for the global medical strategy and implementation and tracking of global activities for a designated disease area(s). Key accountabilities include, but are not limited to, disease area specific Integrated Medical Plan development, including the publication plan, integrated evidence generation plan, global medical launch strategy and execution, scientific leadership, external medical expert engagement, and strategic alignment with commercial and other cross-functional business partners.. This leader reports directly to the VP, Global Medical and is a core member of the Global Medical leadership team. They will lead the global medical affairs team for the designated disease area(s) and represents Medical Affairs in all Global strategic teams with Development and Commercial, including the Disease Strategy Team (DST) to drive cross-functional alignment, anticipate future needs, and contribute to Medical Affairs and Vertex’s long-term success. 

Key Duties and Responsibilities:

Medical Strategy 

• Lead the development, implementation, execution, and communication of the Integrated Medical Plans, including but not limited to medical strategy, global tactical plan, publication, congress and evidence generation plans, in collaboration with Clinical Development, Clinical Operations, HEOR, RWE, Medical Writing, and other internal stakeholders across Vertex  

• Ensure alignment of medical strategy with organizational objectives by integrating individual and disease area team goals with Vertex and DST priorities, and the goals of cross-functional partners 

• Expertly distills insights and actionable outcomes that inform strategy and drive the greatest impact for Medical Affairs  

• Establishes and tracks medical KPIs that demonstrate impact on asset strategy and patient outcomes. 

• Applies structured problem-solving and root cause analysis to identify solutions and make decisions that maximize medical and asset strategy  impact 

• Able to identify what is important and impactful to medical and the wider organization, prioritize competing demands and communication to key stakeholders 

• Accountable for development of the global DA budget, management of funds allocation, and associated tracking to ensure alignment with Medical Affairs priorities and efficient resource allocation 

Scientific Excellence 

• Serve as product and disease area expert and Global Medical primary contact point for all global disease area related issues with the external community and internally at Vertex 

• Able to lead development of peer reviewed publications, congress presentations and evidence generation to inform clinical practice 

• Lead the development of global scientific communications and materials including materials for global led symposia, advisory boards, and training. 

• Accountable for medical review of assigned brand related content and global medical content aligned with Vertex SOPs 

External Partnerships 

• Represent Vertex at scientific and medical forums, including medical education forums, scientific societies, patient advocacy groups, and congresses. 

• Accountable for engaging and cultivating professional relationships with leading global key thought leaders (TL) to gain greater understanding of the disease area, and insights into unmet patient needs 

Medical Communication 

• Tailors communication to stakeholder needs, building trust and understanding across diverse audiences. 

• Deliver external presentations (advisory board meetings, symposia, other medical education meetings) to enhance the medical knowledge of pipeline and marketed products, as required and in accordance with relevant regulations and procedures 

• Support disease area training across the company as required 

• Responsible for medical interpretation of data (clinical trials, registries, published literature, etc.) for pipeline therapies and marketed medicines 

Regional Medical and Cross Functional Collaboration 

• Accountable for the medical comp