Senior Associate Scientist, Non-Viral Gene Editing Platforms

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Position Responsibilities

In this role as a Sr. Associate Scientist Non-Viral Gene Editing Platforms, the ideal candidate:

• Spends a majority of the time working in the lab independently executing experiments and recording detailed ELN entries

• Proactively communicates and coordinates activities with other team members to achieve results

• Works diligently within the team to develop and optimize non-viral gene editing platform protocols and reagents

• Routinely generates CAR-T cells including non-viral gene editing, expansion, and cryopreservation of engineered cells

• Analyses and interprets experimental data

• Thoroughly characterizes engineered CAR-T cells including phenotypic analysis via flow cytometry, in vitro cytotoxicity assays (e.g., Incucyte), and genomic DNA extraction for downstream molecular analysis

• Leverages their knowledge of molecular biology for in silico design of DNA sequences of large and complex engineered cargo in coordination with the molecular engineering team

• Actively troubleshoots routine problems and initiatives related to continuous improvement or development of new approaches / technologies

• Makes decisions that require choosing between limited alternatives to resolve problems of varying levels of complexity

Experience

Basic Qualifications:

• Bachelor’s Degree

  • 4+ years of academic and / or industry experience

Or

• Master’s Degree

  • 2+ years of academic and / or industry experience

Preferred Qualifications:   

• Experience culturing T cells including aseptic technique, T cell activation, and maintenance of primary cell cultures

• Experience with multi-color flow cytometry including complex panel design and multi-parameter data analysis (FlowJo)

• Hands-on experience with gene editing technologies (CRISPR/Cas9 preferred)

• Strong knowledge of molecular biology and prior experience with DNA design tools such as Benchling, SnapGene, etc.

• Ability to effectively multi-task, independently organize time, and can develop timelines and deliver results accordingly

• Demonstrated ability to work within a team and thrive in a fast-paced and ever-changing environment

• Detail oriented with excellent verbal and written communication skills and careful documentation (prior ELN experience a plus)

The starting compensation for this job is a range from $100,480 - $121,800, plus incentive cash and stock opportunities (based on eligibility). 

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience. 

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site. 

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and opti