Senior Research Technician

Department

BSD MED - Hematology and Oncology - Tsanov Research Staff

About the Department

The Section of Hematology/Oncology in the Department of Medicine has a long-standing tradition of excellence in research-based patient care, scientific and clinical discovery, and outstanding education of trainees at various career stages. Consistently ranked as one of the top cancer programs in the country, the Section includes nationally and internationally recognized faculty with expertise in all major types of malignancies, blood disorders, and experimental therapeutics.

Within the Section, the Tsanov laboratory investigates metastatic disease – the major cause of cancer-related deaths. The overall goal of the laboratory’s research is to elucidate mechanisms that sustain metastatic tumors and to identify related vulnerabilities that can be therapeutically targeted. The laboratory focuses on pancreatic and gastric adenocarcinomas, and integrates innovative mouse models, functional genetics tools and multiomic approaches to dissect the interplay of genetic, epigenetic and microenvironmental factors in metastatic tumors.

Job Summary

The Senior Research Technician will be involved in a cutting-edge cancer research program that uses techniques related to genetics, molecular, cellular and cancer biology. They will be involved in projects that use mouse and cell culture-based model systems, and will provide support for all aspects of research in the Tsanov laboratory. The day-to-day work will involve molecular cloning, tissue culture, animal care and procedures, sample processing and analysis, in close collaboration with a team of dedicated colleagues. Additional duties include aspects of laboratory management and training of more junior lab members. The ideal candidate is significantly independent and has a strong work ethic, excellent organizational skills, relevant prior research experience, and willingness to learn new techniques.

Responsibilities

• With a moderate level of direction, performs lab and/or research-related duties and tasks. Helps develop, design, and conduct research projects according to plan.

• Analyzes and maintains data and specimens. Conducts literature reviews. Assists with preparation of reports, manuscripts, and other documents.

• Cell culture, including adherent and suspension cells, transfections, transductions, gene editing.

• Assists in maintaining mouse colony, including genotyping and general husbandry, and mouse procedures (injections, treatments, imaging, tissue collection, and/or surgeries after appropriate training).

• Assists with molecular and cellular biology techniques, including cloning, DNA/RNA/protein isolation, PCR, qRT-PCR, next-generation sequencing (DNA/RNA/ATAC-seq), reporter gene assays, Western blot, immunostaining, microscopy, flow cytometry (after appropriate training).

• Assists with general lab duties, including ordering and maintaining equipment and supplies.

• Ensures project compliance with different policies, procedures, directives, and mandates.

• May train or orient less experienced lab personnel.

• Supports data collection and analytical needs of research projects. Conducts literature reviews and helps write reports and manuscripts. Ensures project compliance with different policies, procedures, directives, and mandates.

• Takes responsibility for the following laboratory duties: recognizing abnormal results and varying conditions or procedures to correct problems; setting up and performing experiments. Analyze the meaning, significance, causes, and effects of the subject.

• Performs other related work as needed.

Minimum Qualifications

Education:

Minimum requirements include a college or university degree in related field.

Work Experience:

Minimum requirements include knowledge and skills developed through 2-5 years of work experience in a related job discipline.

Certifications:

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Preferred Qualifications

Education:

• Advanced degree in Genetics, Molecular Biology, Cell Biology, or a related field.

Experience:

• 3 plus years of experience as a Research Technician in academia.

• Experience with research techniques or methods relevant to the lab.
   

Preferred Competencies

• Knowledge in relevant scientific field(s).

• Strong organizational skills, administrative skills, and time management skills.

• Strong analytical skills, problem-solving skills, and attention to detail.

• Adaptability and willin