Senior Scientist, TCR Gene Therapy

Senior Scientist, TCR Gene Therapy

Gaithersburg, MD

Are you passionate about eradicating cancer and highly motivated to explore T-cell receptor (TCR) gene therapy approaches? We are seeking a Senior Scientist to join our Oncology R&D team. This is your chance to work on the next generation of new drug modalities and experience more than traditional molecules.

Accountabilities:

In this role, you will be responsible for developing and leading pipeline tumor-specific TCR-T therapy projects. You will also be tasked with developing strategies to increase antitumor potency of TCR-engineered T cells, critically analyzing and interpreting data, and contributing to study reports and presentations.

Essential Skills/Experience:

• PhD or MD in relevant subject area with at least 5 years of experience in immunology
• Track record of innovation in TCR-T immunotherapy research
• Experience in culturing and expanding human T cells using a variety of methods
• Expertise in genetically modifying T cells
• Extensive experience in common immunological assays
• Great attention to detail
• Excellent communication and organizational skills
• Highly developed problem-solving skills
• Ability to motivate and lead a small team
• Ability to drive projects to completion

Desirable Skills/Experience:

• Molecular biology skills
• Experience in human adoptive cell therapy trials
• Expertise in a wide range of gene engineering platforms
• Experience in preclinical mouse models of adoptive cell therapy
• Experience in cell therapy development in a biotech/pharma setting

At AstraZeneca, we are pioneers, making bold moves that transform the way cancer is treated and truly improve patient outcomes. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate, and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. It's science with an impact-making a difference for patients and people around the world.

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

So, what’s next?

Are you ready to push the boundaries of science to change the practice of medicine? Apply now and join us in our mission to eliminate cancer as a cause of death!

If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: November 28, 2024

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more-

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing ind