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Senior Scientist, Discovery Biology, Oncology Thematic Research Center

Bristol Myers Squibb
United Statesfull_timeVerifiedPosted 8 Oct 2025
💰 $159,454/yr($131,590/yr$159,454/yr)

About the role

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

We are seeking an innovative and motivated immunologist to advance our portfolio of pioneering T cell engager therapeutics to treat cancers. The successful candidate will join the Discovery Biology Team within the Oncology Thematic Research Center at Bristol Myers Squibb in Seattle, WA. The qualified candidate will provide expertise in immunology and will join a multidisciplinary, groundbreaking team driving projects from discovery through IND. Using their knowledge in T cell immunology, the candidate will have the opportunity to identify and validate novel targets and design novel assay systems to enable next-generation engager cancer therapeutics. This scientist will work in a highly collaborative, dynamic, fast-paced environment involving multiple teams across the company.

In the role as a Senior Scientist within Discovery Biology, the ideal candidate will:

  • Identify and validate novel targets for development of T cell engagers.
  • Independently design, develop and execute novel in vitro and ex vivo cell-based assays/models to evaluate the efficacy and specificity of T cell engagers.
  • Apply knowledge of T cell biology to develop next-generation T cell engagers with improved efficacy and safety profiles.
  • Design and implement critical studies required to drive hypothesis-driven research.
  • Collaborate across multiple projects / roles in a matrixed environment.
  • Present complex concepts to a range of audiences including governance and full team project meetings.
  • Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders

Basic Qualifications:

  • Bachelor’s Degree
    • 6+ years of relevant academic and / or industry experience

Or

  • Master’s Degree
    • 4+ years of relevant academic and / or industry experience

Or

  • Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field
    • 2+ years of relevant academic and / or industry experience

Preferred Qualifications

  • Ph.D. or equivalent advanced degree in immunology, immuno-oncology, tumor immunology, or a related field
    • 2+ years of relevant  academic and / or industry experience
  • Knowledge of T cell biology and relevant in vitro assay systems and experience with transformed tumor cells is strongly preferred.
  • Experience with technologies typically employed to engineer cell lines and assess immune cell function including but not limited to subset of CRISPR, RNAi, Luminex, MSD, IncuCyte-based assays, multi-parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies. 
  • Demonstration of hypothesis-driven, in-depth, innovative thinking and experimentation
  • Self-motivated and focused with project management-oriented thinking; able to work on multiple projects in a matrix environment
  • Ability to communicate well with peers, supervisors, and governance committees.
  • Strong problem-solving skills and understanding of complex scientific principles.
  • Requires strong organizational skills to ensure thorough and timely documentation of experiments, and preparation of data for compiling reports for both internal and external documents.
  • Experience with antibody drug discovery and target identification / validation is an advantage.

#LI-ONSITE

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

Seattle - WA: $1

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Company

Bristol Myers Squibb

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