Executive Medical Director, US Medical Affairs Lead

Career Category

Medical Affairs

Job Description

JOIN AMGEN’S MISSION OF SERVING PATIENTS

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year.

As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Executive Medical Director, US Medical Affairs Lead

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What you will do

Let’s do this. Let’s change the world. In this vital role as Executive Medical Director, US Medical Affairs Lead, you will be accountable for the development and execution of the US medical affairs strategy for the Thyroid Eye Disease franchise (teprotumumab-trbw/TEPEZZA) and pipeline with the objective of maximizing Amgen’s value proposition.

TEPEZZA® (teprotumumab-trbw) is the first and only FDA-approved therapy for Thyroid Eye Disease (TED), a serious, progressive, and potentially vision-threatening autoimmune condition. TEPEZZA is a fully human monoclonal antibody that targets and inhibits the insulin-like growth factor-1 receptor (IGF-1R), a key driver of TED pathophysiology. By blocking IGF-1R signaling, TEPEZZA has been shown to reduce inflammation, orbital tissue expansion, and proptosis, improving both functional and quality-of-life outcomes.

Clinical studies have demonstrated its efficacy and safety across patients with active and chronic low–clinical activity score (CAS) TED, highlighting its broad impact on disease management. TEPEZZA represents a transformative advancement for patients, with ongoing research exploring its potential in other IGF-1R–mediated conditions.

At Amgen, we are deeply committed to advancing innovative therapies for rare diseases, where the need is greatest and the impact can be life changing. The development and success of TEPEZZA exemplify this mission, underscoring our dedication to bringing breakthrough treatments to patients who have long been underserved

Responsibilities:

• Developing the US medical strategy for teprotumumab through deep understanding of medical practice to maximize access and reimbursement

• Contributing to the product strategy for teprotumumab and TED franchise pipeline

• Developing and leading external stakeholder plan, management, communication, evidence generation, and medical education

• Developing and leading execution of a US medical communication strategy, including clinical narrative framework, scientific platform, core content, congresses, and publications

• Engaging US external stakeholders to strengthen the understanding of the unmet need and medical value of Teprotumumab and TED franchise pipeline

• Elevating Amgen’s reputation as a science-based and patient focused reliable partner

• Partnering on evidence generation and ensuring key regional/local needs are addressed

• Providing medical insights and advice internally

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What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The candidate we seek is an experienced leader with the following qualifications.

Basic Qualifications:

• Doctorate degree & 6 years of directly related experience OR

• Master’s degree & 10 years of directly related experience OR

• Bachelor’s degree & 12 years of directly related experience AND

• 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

Preferred Qualifications:

• MD, PharmD or PhD degree from an accredited school

• 3 years of Medical Affairs experience in Immunology, ophthalmology or pharmacology

• Rare disease knowledge and experience

• 5 or more years of Medical Affairs experience in the biopharmaceutical industry (biotech, pharmaceutical or CRO) that includes collaborations with integrated delive