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Sr. Project Manager
SystimmuneUnited Statesfull_timeVerifiedPosted 23 Jun 2026
💰 $85,000/yr($60,000/yr – $85,000/yr)
About the role
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
We are seeking a Senior Project Manager, R&D to support cross-functional planning and execution for oncology biologics programs from early discovery through IND-enabling activities and support of IND submission. This role will partner closely with Research, Translational Sciences, Nonclinical, Regulatory, Clinical Pharmacology, and external partners to drive integrated development strategy, stage-appropriate planning, risk management, and operational execution.
The ideal candidate brings strong biotech or biopharma drug development experience, excellent cross-functional leadership skills, and a deep understanding of the milestones, dependencies, and decision points required to advance innovative biologics programs into the clinic. This individual will serve as a strategic and operational hub for assigned programs, ensuring alignment, accountability, and timely progress across the portfolio. A key aspect of this role is the effective use of meeting management to strengthen stakeholder integration, communication, decision-making, and execution across internal and external teams.
Key Responsibilities
We are seeking a Senior Project Manager, R&D to support cross-functional planning and execution for oncology biologics programs from early discovery through IND-enabling activities and support of IND submission. This role will partner closely with Research, Translational Sciences, Nonclinical, Regulatory, Clinical Pharmacology, and external partners to drive integrated development strategy, stage-appropriate planning, risk management, and operational execution.
The ideal candidate brings strong biotech or biopharma drug development experience, excellent cross-functional leadership skills, and a deep understanding of the milestones, dependencies, and decision points required to advance innovative biologics programs into the clinic. This individual will serve as a strategic and operational hub for assigned programs, ensuring alignment, accountability, and timely progress across the portfolio. A key aspect of this role is the effective use of meeting management to strengthen stakeholder integration, communication, decision-making, and execution across internal and external teams.
Key Responsibilities
- Lead cross-functional project planning and execution for oncology biologics programs spanning target/lead discovery, candidate selection, IND-enabling studies, CMC development, and IND submission
- Build, maintain, and drive integrated project plans, timelines, milestones, scenarios, and critical path analyses across multiple functional areas
- Partner with program leaders and functional heads to define development strategy, key objectives, deliverables, governance milestones, and resource assumptions
- Facilitate cross-functional team meetings, sub-team meetings, and governance reviews; document decisions, action items, risks, and next steps
- Identify interdependencies, operational risks, and potential bottlenecks early; drive mitigation plans and escalate issues appropriately
- Ensure alignment across Research, Nonclinical, CMC, Regulatory, Clinical, Biomarker/Translational, Quality, and partner organizations
- Drive program team preparedness for major stage gates, including candidate nomination, development candidate selection, IND-enabling study initiation, and IND submission
- Support budget planning, resource tracking, and external partner/CRO coordination as needed
- Develop concise and decision-oriented communications for senior leadership, governance bodies, and key stakeholders
- Track progress against program goals and proactively highlight deviations, tradeoffs, and decision needs
- Promote disciplined program management practices, clear accountability, and efficient team operations
- Contribute to portfolio planning and cross-program prioritization discussions where appropriate
- Help apply and improve R&D project management tools, templates, dashboards, and best practices
- Drive scalable adoption of AI-enabled and digital program management practices—including automation, dashboards, AI-assisted synthesis, standardized workflows, and data-driven reporting—to improve planning, meeting effectiveness, action tracking, knowledge management, risk identification, portfolio governance, and cross-functional execution while ensuring human oversight, data integrity, and compliance.
- Bachelor’s degree in life sciences, biomedical sciences, chemistry, engineering, or related field
- 8+ years of relevant experience in biotech, biopharma, or related life sciences industry
- 5+ years of project or program management experience supporting drug discovery
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