Director Clinical Regulatory Affairs (US)

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!  

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. 

Why Join Us? 

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy. 

• Collaborative Culture: Be part of a diverse team dedicated to your professional growth. 

• Global Impact: Contribute to therapies that make a lasting impact on patients globally. 

The Director of Clinical and Regulatory Affairs (US) serves as the clinical regulatory lead for assigned programs within the cell and gene therapy portfolio at Immatics.  This role owns and executes US clinical regulatory strategy, independently leading cross-functional efforts to advance development programs with precision, compliance, and speed.  The Director anticipates regulatory risk, drives mitigation strategy, and operates as a trusted strategic partner to senior leadership.   

FLSA Classification: Salaried, Exempt  

Salary: $221,000 - $253,830
Schedule: 8:00 AM – 5:00 PM; Monday to Friday; Remote
Reports to: Senior Director, Regulatory Affairs  
Location: Remote or 13203 Murphy Road Suite 100 Stafford, TX 77477  

What You’ll Do: 

As Director of Clinical and Regulatory Affairs, you will:  

• Develop, own, and continuously refine US clinical regulatory strategy aligned with global development plans and corporate objectives 

• Serve as Regulatory Functional Lead for assigned US clinical programs, ensuring regulatory considerations are embedded in development decisions 

• Lead preparation, strategy development, and execution of FDA interactions (e.g., INTERACT, pre-IND, Type B/C meetings, End-of-Phase meetings, pre-BLA meetings), including brie