Principal Associate Scientist, Alzheimer's Disease

Company Description

At Biogen, we offer a workplace that is unique, connected, resilient and impactful. Our purpose to find cures for rare diseases is a unique focus within our industry. We are connected as a team by this shared purpose, the pride we have in our work, and the inspiration we obtain from the lives we’re changing. We are resilient as we overcome obstacles, following the science to deliver for our patients. Most of all, our work allows us to have an impact. An impact on our patients’ lives and on changing the course of medicine.   

Job Description

About This Role

The successful candidate will be part of a team involved in target discovery and validation studies, in vitro assay development activities, compound screening and characterization using a wide variety of analytical techniques.

 What You’ll Do

• Planning, designing, and executing experiments semi-independently in consultation with scientists in the group
• Performing a variety of in vitro and cell-based assays
• Conducting in vivo studies using mouse models of Alzheimer’s Disease and other Neurodegenerative Disorders
• Analysis, interpretation, and presentation of experimental results

Who You Are

You have strong expertise with in vivo studies. Experienced with molecular, biochemical and cell biological techniques, and cellular assay development/validation.

Qualifications

Required Education/Skills

• BS degree with 4+ years or MS degree with 2+ years of relevant bench experience in academia or biopharmaceutical industry
• In vivo experience with mouse models handling and takedowns
• Cell culture and aseptic techniques, including IPSC neurons, primary neuronal culture
• Biochemistry techniques (ELISA, WB, IP, protein extraction)
• Possess good understanding of basic neurobiology of neurodegenerative diseases and mechanisms of neurodegeneration

Preferred Education/Skills

• BS with 7 years of experience or MS degree with 3 year of relevant bench experience
• In vivo experience with dosing and stereostatic surgery
• Molecular biology and cell biology (required): Technical background should include cloning, DNA manipulation, qRT-PCR and other methods of RNA quantitation; Transfection techniques, generation of stable cell lines (Overexpression, knockdown/out, and coding variants);

Additional Information

Why Biogen?

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.

All your information will be kept confidential according to EEO guidelines.