Senior Scientist

Job Summary: Provide bioanalytical method development for quantitative analysis of test compounds in biological matrices obtained from a variety of studies for non-GLP and GLP regulated studies.

Essential Functions:

• Develop, optimize, and validate LC-MS/MS bioanalytical methods within biological matrices with high technical level report writing upon completion of study
• Develop and implement assays for bioanalysis of small molecules, peptides, and amino acids in both a non-GLP regulated and GLP regulated environment
• Perform instrumentation qualifications, calibrations, and verifications
• Use and maintenance of Sciex (Analyst® Software) and Thermo Scientific (Xcalibur® software) triple quadrupole mass spectrometers
• Experience in PK study design, data interpretation, and analysis

Additional Responsibilities:

• Good written and oral communication, and organizational skills are mandatory.

Job Qualifications: General Knowledge, Skills, and Abilities (KSA’s) required

▪ Experience with method development, executing, and troubleshooting LC-MS/MS assays
▪ Experience with sample extraction techniques such as PPT, SLE, and derivatization
▪ Time management, organizational skills, and a high level of attention to detail
▪ Ability to work effectively as both an individual contributor and in a collaborative team setting.
▪ Knowledge regarding troubleshooting techniques of bioanalytical assay method development, qualification, validation, and sample analysis
▪ Experience in the application of Good Laboratory Practices (GLP) to provide accurate documentation of analytical results
▪ Experience using laboratory equipment including HPLC-MS/MS, Precellys® tissue homogenizer and routine equipment used for sample preparation.
▪ Knowledge of or capability to learn Analyst®, Excalibur®, LCQuan® and Microsoft® Office software platforms.
▪ Knowledgeable in the application of Good Laboratory Practices (GLP) to provide well-regulated and accurate documentation of analytical results for inclusion into regulatory documents.

Physical Demands: Physical, Mental and workplace Environment Conditions

▪ Attention to detail regarding safety and accuracy of procedures performed. Lite lifting of up to 20lbs. may be required.
Working Conditions: Workplace Environment Conditions
▪ Position functions are performed in an office and laboratory environment.

Education and Experience:
▪ Position requires a minimum of a Bachelor’s degree in chemistry, biochemistry, biology, pharmacy or a related discipline, plus a minimum 10 years of applicable lab bench experience.

We Offer:
• Medical, Dental & Vision Insurance
• Short and Long Term Disability
• Life Insurance
• Paid Vacation, Holidays, and Sick Time
• 401(k)

Visit us at https://www.pharmoptima.com/

Genesis Pharmoptima is an equal opportunity employer.