Global Commercial Lead, Fetrastobart Vedotin

ROLE SUMMARY

At Pfizer Oncology, we are committed to “Outdo Cancer” by advancing transformative medicines wherever we can make a profound difference in the lives of patients. Today, Pfizer Oncology has an industry-leading pipeline that includes the combined legacy Pfizer and Seagen portfolio across breast, genitourinary, hematology-oncology and thoracic therapeutic areas.  Thoracic represents a crucial component to achieve Pfizer’s overarching strategic ambition in Oncology; thoracic is estimated to represent ~25% of Pfizer Oncology’s 2030 global sales.  Collectively, our focus is on building upon our foundation in lung precision medicine to accelerate new standards of care in broader populations. 

Despite therapeutic advances in lung cancer, there remains significant unmet patient need.  Each year, there are ~2.7 million new lung cancer cases globally.  The lung cancer therapies market is expected to grow from $45B in 2025 to $70B in 2030 globally. Core to Pfizer’s lung cancer strategy is realizing the potential of our first-in-class antibody drug conjugates (ADCs), including fetrastobart vedotin (fetra-v), a PD‑L1–directed, vedotin‑based ADC.  The first commercial launch of fetrastobart vedotin 2L+ NSCLC is being planned for 2028. 

This role provides an excellent opportunity to shape and drive the fetrastobart vedotin global commercial potential and address the significant unmet needs of lung cancer patients.  In Global Marketing, we translate science into value for patients.  Our remit is to own the strategic direction across the asset lifecycle, ensure long-term value creation and preservation, and drive brand consistency across markets and efficiencies in execution. This role will report to the Vice President, Global Franchise Lead for Hematology, Thoracic and Gastrointestinal, and will have both direct and matrix leadership.  Key focus will be to drive commercial thought leadership on fetrastobart vedotin brand strategy and launch strategy to ensure a successful global launch.

The role requires experience in global or US marketing, launch excellence, commercial strategy and market development.

ROLE RESPONSIBILITIES

• Own fetrastobart vedotin global launch strategy inclusive of brand positioning and messaging, market development, customer specific strategies, and country launch sequence.

• Represent Global Commercial voice and point of view on fetrastobart vedotin Global Product Team (GPT) and partner closely with Clinical Development, Regulatory, Global Access & Value, Global Medical Affairs to ensure key opportunities and risks in the clinical development plan meet the target product profile.

• Partner with CSI to drive thought leadership on lifecycle commercial potential, including key risk/opportunity identification that factors competitive landscape dynamics, to ensure value creation for the mid-to-long term horizon

• Contribute to Global Thoracic Commercial Strategy in partnership with fellow Global Commercial Leads to ensure aligned portfolio positioning and brand positioning

• Collaborate effectively with R&D, Regulatory, Global Access & Value, Global Medical Affairs, Customer Analytics & Insights, Finance, PGS, US, and International. 

• Deliver Global Guidance for OP/LRF forecast assumptions, reflective of brand aspiration as well as risk/benefit.

• Lead fetrastobart vedotin Global Governance Team (GGT) and align brand strategies and deliver core promotional resources and tactics to US and International Commercial Office.

• Partner with Global Access Strategy & Pricing and International Commercial Office on global pricing approval decisions and country access strategies that optimize and preserve value of lifecycle.

• Establish core global launch team

• Develop detailed, strategic commercialization roadmaps and plans to ensure launch readiness and appropriate planning assessments by partnering closely with CMO Launch Excellence team.

• Ensure proactive translation of key competitive intelligence insights into action; and prepare senior leadership communications when appropriate.

• Collaborate with PGS on global supply and demand planning, as well as packaging decisions

• Engage, coach and develop others through creation of a high-performance culture focused on Courage, Excellence, Equity and Joy.

• Conduct all activities and makes decisions that are in accordance with Company policies and SOPs, Pfizer Values & global regulatory guidelines, and requests consultation when navigating uncertain situations.

BASIC QUALIFICATIONS

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develo