Vice President/Senior Vice President, Manufacturing Sciences

Overview

Who We Are:

 

At Dendreon, we’re transforming the battle against cancer with personalized immunotherapy. Our flagship product, PROVENGE® (sipuleucel-T), was the first FDA-approved immunotherapy for metastatic castrate-resistant prostate cancer, utilizing a patient’s own immune cells to fight the disease.

 

If you’re driven by the opportunity to make a meaningful impact on cancer patients' lives, we invite you to join our team. With Immunotherapy Manufacturing Facilities in Seal Beach, CA, and Union City, GA, a strong Research & Development group in Seattle, WA, and a highly skilled Commercial team across the nation, Dendreon is at the forefront of cancer treatment innovation.

 

Core Values:

 

• Put Patients First: Every day is an opportunity to improve the lives of those living with cancer.
• Act with Integrity: We commit to transparency, honesty, and always doing what’s right.
• Build Trust: Trust is earned through candid, open communication and a collaborative approach.
• Raise the Bar: We embrace continuous improvement and innovation, always striving to elevate our people.
• Drive Results: We are accountable to each other and deliver success together.

Job Summary:

The Vice President / Senior Vice President, Manufacturing Sciences, provides executive leadership for Dendreon’s Manufacturing Sciences organization across both commercial and CMS/CDMO operations. This role is responsible for end‑to‑end CMC strategy, technical execution, and organizational leadership across advanced therapy platforms.

This role is responsible for leading and integrating:

• Analytical Sciences
• Antigen / Cellular Product Sciences
• Process Development & Process Sciences
• MSAT (Manufacturing Science & Technology) / Tech Transfer
• CMS (Contract Manufacturing Sciences)

NOTE: Title will be commensurate with experience, scope, and demonstrated leadership capability.

Responsibilities

 

• Enterprise Manufacturing Sciences Leadership
  • Lead and integrate all Manufacturing Sciences functions across commercial and CMS programs.
  • Establish technical strategy, organizational structure, and operating model to support both internal pipeline and CDMO growth.
  • Ensure alignment of Analytical, Process Development, MSAT, and Antigen functions with corporate and manufacturing objectives.
• CMC & Technical Strategy
  • Own end‑to‑end CMC strategy for PROVENGE® lifecycle management and new programs.
  • Drive development and commercialization of next‑generation cell therapies, including:
    • mRNA-based platforms
    • CAR‑T and other engineered T-cell therapies
    • Dendritic cell (DC) therapies
    • Solid tumor applications
  • Lead IND, BLA, and post‑approval technical strategy and regulatory interactions.
• Process Development & MSAT Execution
  • Oversee process development, scale‑up, validation, and tech transfer across internal and external manufacturing sites.
  • Ensure successful technology transfer into GMP manufacturing environments.
  • Drive continuous process improvement, robustness, and lifecycle optimization.
• Analytical & Product Sciences
  • Ensure development and execution of analytical strategies supporting release, stability, and comparability.
  • Maintain scientific leadership in cell therapy characterization, potency, and mechanism of action.
  • Support regulatory filings with high‑quality analytical packages.
• CMS / CDMO Manufacturing Sciences
  • Lead Manufacturing Sciences support for Dendreon’s CMS/CDMO business, including:
    • Client onboarding and technical diligence
    • Program feasibility assessments
    • Process development and tech transfer for external partners
    • Partner with BD and Operations to ensure technical readiness and successful execution of client programs
• Cross‑Functional Leadership
  • Partner across Manufacturing, Quality, Regulatory, R&D, and Commercial functions.
  • Ensure alignment between scientific innovation and operational execution.
  • Serve as a key technical advisor to executive leadership.
• Regulatory & Compliance
  • Ensure all activities comply with cGMP and global regulatory requirements.
  • Lead responses to FDA and g