Sr. Director, Global IT Infrastructure & Operations

Overview

Make a global impact—join Repligen.

We’re united by a mission to inspire advances in bioprocessing as a preferred partner in the production of biologic drugs that improve human health worldwide. No matter your role or background, at Repligen you will play a key part in shaping innovative and life-changing therapies. We foster a culture of purpose, collaboration, and shared success—where every voice matters and every contribution drives progress. Join us!

 

About the Role

Repligen is seeking a hands-on, strategic Sr. Director, Global IT Infrastructure & Operations to lead the design, implementation, and ongoing optimization of our global technology infrastructure, end-user services, and site support. This role partners closely with business and IT stakeholders to build an infrastructure & end-user services roadmap aligned to business strategy, while overseeing internal teams, MSPs, and vendors to ensure high-quality, secure, and reliable services.

You will lead and develop a high-performing team, drive continuous improvement, and ensure our infrastructure and end-user computing needs meet the needs of a fast-growing, globally distributed Life Sciences organization.

Responsibilities

 

Key Responsibilities

Strategic Leadership & Architecture

• Develop and maintain the global IT/OT infrastructure architecture aligned to business goals and Life Sciences regulatory requirements.
• Evaluate people, processes, and technologies to ensure an optimal global infrastructure strategy.
• Plan and lead infrastructure and cloud design, upgrades, scalability, and modernization efforts.
• Plan and lead daily IT operations using ITSM practices, collaborating on cybersecurity and compliance, and leading a global team.

Technical & Operational Execution

• Provide Tier 3+ technical leadership for incident and problem resolution.
• Oversee network, cloud, server, data center, storage, telecommunications, industrial control systems, and mobile device management environments.
• Drive daily IT operations using best-practice ITSM frameworks (ITIL). Ensure robust incident, problem, and change management processes are in place to meet stringent Service Level Agreements (SLAs) for critical business systems.
• Ensure continuous monitoring, performance optimization, and documentation standards.
• Drive GxP-compliant infrastructure planning, capacity management, and validation practices.

Vendor, MSP & Budget Management

• Manage MSPs, vendors, and partners to ensure SLA-driven service delivery.
• Lead vendor contract negotiations and performance governance.
• Manage infrastructure  and operations budgets and investment business cases to support new technologies and lifecycle management.
• Ensure vendor and financial management, developing disaster recovery plans, and collaborating with other teams.

Security, Risk & Compliance

• Assess infrastructure risks and implement technologies/processes to mitigate them.
• Ensure compliance with cybersecurity requirements, SOX/GxP standards, and ITIL processes.
• Maintain reliable, repeatable processes for change, patching, provisioning, and validation.

Innovation & Continuous Improvement

• Proven track record of successfully modernizing legacy IT environments, implementing cloud-first strategies, and driving automation and Infrastructure-as-Code principles.
• Research and recommend new technologies that enable innovation, efficiency, or cost optimization.
• Lead infrastructure & operations projects, including new capabilities, site expansions, and facility moves.
• Implement enhancements that improve reliability, performance, and user experience.

Qualifications

 

Required Experience & Qualifications

Experience

• 15 years of progressively responsible experience in IT Infrastructure & Operations leadership.
• Broad technical background covering infrastructure, network, storage, cloud, data center, and virtualization technologies.
• Deep technical knowledge in network and server security; FortiOS and Nutanix highly desirable.
• Strong understanding of ITIL processes (incident, problem, change management).
• Demonstrated success delivering high-quality customer service, including at the executive level.
• Expert knowledge of:
• LAN/WAN, DNS, Active Directory
• Data center operations
• Firewalls/VPNs
• Server setup/configuration/administration
• Virtualization technologies
• Automat