Sr. Distinguished Scientist Clin Pharm

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Pharmacokinetics & Pharmacometrics

Job Category:

Scientific/Technology

All Job Posting Locations:

Beerse, Antwerp, Belgium

Job Description:

Johnson & Johnson -- About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Please note that this role is available across multiple countries and may be posted under different requisition numbers to comply with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s):

US - Requisition Number: R-051910

Switzerland - Requisition Number: R-056533

Belgium - Requisition Number: R-056538

Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission.

Objective of Position

The scientific advisor is responsible for providing scientific advice on global drug development strategies for both small and large molecule compounds in early and late development consistent with principles of Model Informed Drug Development (MIDD) and Clinical Pharmacology considerations.  In this role, the scientific advisor represents CPP at QSTEPS (i.e., Quantitative Sciences Technical Excellence and Program Strategy (QSTEPS) committee) as a core member and provides consultations for study designs, dose selection, and drug development strategy across the JJIM portfolio.  The position leads the organization in planning successful MIDD plans, fostering application of MIDD through implementation of PK, PK/PD, ER, QSP, and MBMA approaches to identify and answer key clinical questions and devise optimized development strategies. 

As part of the disease modeling and innovation team, the scientific advisor assists in the implementation of new methodologies and/or new focus areas for CPP keeping abreast of innovation methodology within clinical pharmacology and pharmacometrics field, in alignment with our focus therapeutic areas. 

Main Accountabilities

•  Represent CPP at QSTEPS and CPP reviews; represent CPP at other governance/review committees, as required.

• Ensure appropriate MIDD planning for projects and in support of our focused disease areas.

• Work with CPP colleagues globally, cross-functionally with other functions in JJIM, and/or externally, as needed, to identify, evaluate, recommend, and implement innovative scientific approaches for CPP colleagues to broaden the understanding of and impact on drug development for small and large molecules.

• Provide scientific advice related to the MIDD approaches including translational pharmacology approaches for compounds in development and to Clinical Pharmacology development plans.

• Assist with implementation of new methodologies and/or new focus areas for CPP. 

• Train, guide and mentor scientists within the global CPP organization to realize their full potential. 

Minimum Qualifications / Experience

• Ph.D. or equivalent, with at least 12+ years of industrial experience in Clinical Pharmacology and/or Pharmacometrics and application of MIDD

Minimum Technical Knowledge and Skills

• Knowledge of drug development of small molecules, monoclonal antibodies