Sr. Medical Director, MD - Translational

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)

About the Role:

Medical expert responsible for the development of early clinical research strategies and independent direction of Phase 1 through Proof-of-Concept clinical studies across all therapeutic areas and modalities at Neurocrine Biosciences. Works with cross-functional project teams (clinical project managers, preclinical/clinical pharmacology, biometrics, regulatory, drug safety) in the creation and execution of early clinical development plans that will ultimately advance Neurocrine's diverse portfolio including small molecules and biologics. Provides expert medical advice to advance early development programs and helps the company navigate the complex early-stage drug development landscape. Works closely with Research and Preclinical Development to develop and implement translational strategies, including biomarkers, necessary for the most effective evaluation of novel molecules in early clinical development across multiple therapeutic areas.

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Your Contributions (include, but are not limited to):

• For assigned early-stage programs across all therapeutic areas, develops clinical development strategies from Phase 1 through Proof of Concept and is accountable for the study design of early clinical trials, leading on the preparation of clinical study synopses and being a major contributor to the writing of protocols/major amendments for diverse modalities including small molecules, antibodies, and peptides

• Represents Medical/Clinical on cross-functional Program Teams as the Early Development Medical Lead across multiple therapeutic areas. Accountable and responsible for the medical input to integrated early development plans and clinical pharmacology strategies that underpin them

• Provides medical leadership and clinical pharmacology expertise to Program Teams. Accountable and responsible for driving the execution of early clinical development plans from first-in-human through Proof of Concept studies

• Develops and implements Phase 1 and early Phase 2 study protocols in conjunction with multidisciplinary Development Teams, with expertise in study d