Senior Associate Scientist, ADC Discovery (non-PHD)

Use Your Power for Purpose

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives.  As a Senior Associate Scientist, you will be at the forefront of our mission, contributing to the development of innovative therapies that have the potential to transform patient care. We are seeking a highly capable Biochemist or Chemist to assist in automated bioconjugation and characterization of antibody-drug conjugates (ADCs) as part of the core conjugation group within Discovery Research. This person will play a critical role in supporting preclinical efforts to develop novel antibody-based therapeutics.

What You Will Achieve

In this role, you will:

• Perform daily operation of Tecan and other automated liquid handlers for high-throughput conjugation of ADCs and sample analysis.

• Synthesize novel Antibody Drug Conjugates (ADCs), including purification and characterization of ADCs using established and experimental methodologies.

• Conduct analytical characterization of antibodies and ADCs including HPLC, LC/MS and spectroscopy

• Collaborate on project teams, present data and demonstrate strong communication skills.

• Data and report generation including regular review of data with manager, project leads and other research associates.

• Evaluate new technologies and/or lab efficiencies

• Prepare critical reagents and maintain inventories

• Perform routine laboratory cleaning and equipment maintenance

Here Is What You Need (Minimum Requirements)

• Bachelor's degree with 3+ years relevant experience or M.S. degree with relevant experience; or equivalent.

• Degree in relevant scientific discipline such as biochemistry, chemistry or related field

• Minimum of 2 years post-baccalaureate lab experience in an academic or industry environment.

• Experience operating automated liquid handlers

• Experience performing protein purification and liquid chromatography techniques

• Detail-oriented with strong analytical, organizational and multi-tasking skills

• Ability to perform routine tasks independently and commitment to high quality analysis and documentation

• Willingness to work with potent cytotoxic compounds, following safety protocols

Bonus Points If You Have (Preferred Requirements)

• Hands-on experience performing analytical HPLC chromatography of proteins and UV spectroscopy

• Analytical LC/MS experience

• An ideal candidate will have previous experience performing bioconjugation techniques

• Knowledge of protein stability and formulation

• Prior experience working with electronic lab notebooks and/or LIMS systems

• Ability to work collaboratively in a team environment

• Excellent organizational and time management skills

  
 

PHYSICAL/MENTAL REQUIREMENTS

Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis.

Additional Information:

• Work Location Assignment: On Premise
• Last Day to Apply: April 29, 2025

The annual base salary for this position ranges from $66,500.00 to $110,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

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